Amidinopenicillanic acid derivative with broad spectrum antibacterial action. It is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United...
- Mechanism
- Curator reviewed
Amdinocillin is a stong and specific antagonist of Penicillin Binding Protein-2 (PBP 2). It is active against gram negative bacteria, preventing cell wall synthesis by inhibiting the activity of PBP2. PBP2 is a peptidoglycan elongation initiating enzyme. Peptidoglycan is a polymer of sugars and amino acids that is the main component of bacterial cell walls.
- Primary indication
- Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species.Curator reviewed
- Formula / weight
- C15H23N3O3S · 325.426 g/mol (avg)
- Also known as
- Mecillinam · Penicillin HX
- Code names
- FL-1060 · RO 10-9070
Resolves to
BWWVAEOLVKTZFQ-ISVUSNJMSA-NSMILES[H]C(=N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@]12[H])N1CCCCCC1What you can answer from here — as of September 12, 2026
Which drugs share a target with Amdinocillin, and which of those have an active Phase 3 trial?
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