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Displaying results 321 - 330 of 9431 in total
  1. Drug

    Inolimomab

    go.drugbank.com/drugs/DB15628
    Investigational

    Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.[A241385]

    Synonyms: Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain), disulfide with mouse monoclonal B-B10 kappa-chain, dimer
  2. Drug

    Pramipexole

    go.drugbank.com/drugs/DB00413
    ApprovedInvestigational

    Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). … In addition to the above FDA approval for Parkinson's Disease, pramipexole was also approved by the FDA in 2006 for the treatment of Restless Legs Syndrome (RLS) [A176873].

    Categories: Nonergot-derivative Dopamine Receptor AgonistsProducts: MIPEXOBEX TM 1.0 MG, MIPEXOBEX TM 0.25 MG
  3. Drug

    Mapatumumab

    go.drugbank.com/drugs/DB18945
    Investigational

    Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).

    Synonyms: Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receptor 4)) (human monoclonal trm-1 heavy chain), disulfide with human monoclonal trm-1 .lambda.-chain, dimer, Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy chain), disulfide with human monoclonal trm-1 .lambda.-chain, dimer
  4. Drug

    Etevritamab

    go.drugbank.com/drugs/DB17211
    Investigational

    Synonyms: anti-EGFRvIII x anti-CD3 bispecific T cell engager antibody construct, IMMUNOGLOBULIN SCFV-SCFV, ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND ANTI-(HOMO SAPIENS CD3E
  5. Drug

    Anti-CD5 CAR T-cell therapy

    go.drugbank.com/drugs/DB17279
    Investigational

    Synonyms: chimeric antigen receptor (CAR) directed against the target protein CD5, CD5CAR-T
  6. Drug

    Pulocimab

    go.drugbank.com/drugs/DB18938
    Investigational

    Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma).

    Synonyms: Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ak109 .gamma.1-chain), disulfide with human monoclonal ak109 .kappa.-chain, dimer
  7. Drug

    Helium

    go.drugbank.com/drugs/DB09155
    ApprovedInvestigationalVet approved

    Helium is a second most abundant chemical element in the universe with symbol He and atomic number 2. … It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table.

    Mixtures: Co-HE-O2-N2 MixtureSynonyms: [He]
  8. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]

    Products: Doxy 100(tm) Doxycycline, DOXYCYCLIN AL 100 T
  9. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    Approved

    Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass [L1801]. Docusate can be orally or rectally administered. … However the effectiveness of docusate in treating constipation remains unclear, as several studies report docusate to be no more effective than placebo for increasing the frequency of stool or stool softening

    Mixtures: Tl-hem 150, TL-SelectProducts: H E B Stool Softener laxative, Sirop Docusate De Sodium USP 20mg/5ml
  10. Drug

    Unoprostone

    go.drugbank.com/drugs/DB06826
    ApprovedWithdrawn

    Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.