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Baclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalBaclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.
Synonyms: DL-4-Amino-3-p-chlorophenylbutanoic acid, beta-(Aminomethyl)-p-chlorohydrocinnamic acidProducts: Ava-baclofen, BACLOFEN AL 25MG TABLETTENSilver
go.drugbank.com/drugs/DB12965ApprovedInvestigationalSilver exists as a pure elemental form, alloy with other metals, and mineral. … Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity.
Products: Ave SilvergenNizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Categories: P-glycoprotein substratesProducts: Axid Ar, AXID 25 MG/ML IV IMF. ICIN ENJ. AMPUL, 5 ADETAgomelatine
go.drugbank.com/drugs/DB06594ApprovedInvestigationalAgomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: AGOMELATIN AL 25MG FTAAmorolfine
go.drugbank.com/drugs/DB09056ApprovedWithdrawnAmorolfine is marketed as Curanail, Loceryl, Locetar, and Odenil. … Amorolfine or amorolfin, is a morpholine antifungal drug that inhibits the fungal enzymes D14 reductase and D7-D8 isomerase.
Products: LOCERYL® LACA PARA UÑAS AL 5%, AMOROLFINE NAIL LACQUER 5%W/VNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigationalNortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA).
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamineValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigationalARBs such as valsartan have been shown in a number of large-scale clinical outcomes trials to improve cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of … [A174124] Valsartan is generally well-tolerated with a side-effect profile superior to that of other antihypertensive drugs.[A174130,A174133]
Mixtures: VALSARTAN COMP PU 160/12.5, VALSARTAN COMP PU 160/12.5Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsCrotamiton
go.drugbank.com/drugs/DB00265ApprovedCrotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor.
Categories: Compounds used in a research, industrial, or household settingProducts: A-Bite Cream, CROTAMITON LOCION AL 10 %Cilostazol
go.drugbank.com/drugs/DB01166ApprovedInvestigationalCilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: CILOSTAZOL AL 50MG TAB, CILOSTAZOL AL 100MG TABBrinzolamide
go.drugbank.com/drugs/DB01194Approved[A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination product with brimonidine tartrate. … [L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesProducts: BRINZOLAMID AL 10MG/ML