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Etomidate
go.drugbank.com/drugs/DB00292ApprovedInvestigationalImidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Categories: Adrenergic alpha-2 Receptor Agonists, Heterocyclic Compounds, 1-RingSynonyms: (R)-(+)-1-(α-methylbenzyl)imidazole-5-carboxylic acid ethyl ester, (+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylateBenzethonium
go.drugbank.com/drugs/DB11125ApprovedIt is shown to be effective in mediating its antimicrobial action against bacteria, fungi, mold and viruses. … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments.
Products: 3 in 1 First Aid Wound Care, Charm Tex 3 IN 1 Antibacterial Shave Gel Body WashProstaglandin E synthase 3
go.drugbank.com/bio_entities/BE0002480TargetHumansMolecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory
Polypeptides: Prostaglandin E synthase 3Centromere-associated protein E
go.drugbank.com/bio_entities/BE0003434TargetHumansPlays a role in spindle assembly checkpoint activation (SAC) via its interaction with BUB1B resulting in the activation of its kinase activity, which is important for activating SAC. … Suppresses chromosome congression in NDC80-depleted cells and contributes positively to congression only when microtubules are stabilized (PubMed:25743205).
Polypeptides: Centromere-associated protein ESynonyms: CENP-E, Centromere protein EBotulinum neurotoxin type E
go.drugbank.com/bio_entities/BE0009355TargetClostridium botulinumPrecursor of botulinum neurotoxin E which has 2 coreceptors; complex polysialylated gangliosides found on neural tissue and specific membrane-anchored proteins found in synaptic vesicles. … Requires trypsinization and reduction before it can be used in assays in vitro (PubMed:8294407).
Polypeptides: Botulinum neurotoxin type ESynonyms: BoNT/E, Bontoxilysin-EInterleukin-17 receptor E
go.drugbank.com/bio_entities/BE0017393TargetHumansMay be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms.
Polypeptides: Interleukin-17 receptor ESynonyms: IL-17 receptor EInsulin glulisine
go.drugbank.com/drugs/DB01309ApprovedIf left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able
Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersProducts: APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL, Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled penKetoprofen
go.drugbank.com/drugs/DB01009ApprovedInvestigationalVet approvedKetoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Mixtures: DOLFORT-DECategories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesGadoteric acid
go.drugbank.com/drugs/DB09132ApprovedInvestigationalGadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). … associated tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with disruption of the blood-brain barrier (BBB) and/or abnormal vascularity.
Categories: Compounds used in a research, industrial, or household settingSynonyms: [2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-κ4N1,N4,N7,N10)tetraacetato(3−)]gadoliniumMethoxy polyethylene glycol-epoetin beta
go.drugbank.com/drugs/DB09107ApprovedInvestigationalMethoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. … ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Categories: Compounds used in a research, industrial, or household settingProducts: MIRCERA 360 MCG/0.6 ML SC/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, MIRCERA 100 MCG/ML SC/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET