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Atidarsagene autotemcel
go.drugbank.com/drugs/DB17538ApprovedInvestigationala lentiviral vector encoding the human arylsulfatase A (ARSA) gene. … [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic
Synonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene, Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid sequenceIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigationalIsotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]
Synonyms: Neovitamin A acid, 13-cis-Vitamin A acidMixtures: ISOTREXIN JEL, 30 G, ETREXİN % 2 + % 0.05 JELCollagenase clostridium histolyticum
go.drugbank.com/drugs/DB00048ApprovedInvestigational[L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women. … Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum.
Synonyms: Clostridiopeptidase AMianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnA tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 3-RingPepsin
go.drugbank.com/drugs/DB13198ApprovedWithdrawnStimulation of the pancreas and therefore enzymatic digestion of food is a tightly controlled and is a hormonally mediated process. … Interestingly, it has been used as a marker for laryngopharyngeal reflux (LPR), which is a common illness of otolaryngology (ear, nose and throat specialist) visits [A32604].
Synonyms: Pepsin AMixtures: PEPZAN 225 MG/225 MG FİLM TABLET, 20 ADET, Debiline HTrazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigational[T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms, or insomnia, which are commonly associated with SSRI and SNRI therapy. … [T646] Trazodone acts on various receptors, including certain histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a narrow range of neurotransmitters
Synonyms: 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneCategories: P-glycoprotein inducers, Cytochrome P-450 SubstratesNeisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen
go.drugbank.com/drugs/DB14427ApprovedInvestigationalNeisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Synonyms: Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigenMixtures: MENVEO®, MENVEO®Mirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigationalMirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy.
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine, 6-AzamianserinCategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor AntagonistsSuccinyl-Coenzyme A
go.drugbank.com/drugs/DB03699ExperimentalSynonyms: Succinyl-Coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring