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Encainide
go.drugbank.com/drugs/DB01228ApprovedWithdrawnEncainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack.
Categories: Antiarrhythmics, Class I, Cytochrome P-450 SubstratesSynonyms: 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide, (±)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamidePioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigationalPioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus. … presence of multiple adverse effects and warnings regarding their use (e.g. congestive heart failure, bladder cancer) and the availability of safer and more effective alternatives for patients with type 2
Mixtures: DUERID 30/4 MG TABLET, 30 ADET, DUERID 30/2 MG TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesMelphalan
go.drugbank.com/drugs/DB01042ApprovedInvestigationalMelphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. … [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.
Synonyms: 4-(Bis(2-chloroethyl)amino)-L-phenylalanine, 4-[bis(2-chloroethyl)amino]-L-phenylalanineProducts: ALKERAN® 2 MG TABLETAS, Alkeran 2 mg - FilmtablettenLevonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigationalA subdermal implant of levonorgestrel that slowly releases the hormone over a long-term period is also available. … [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD.
Mixtures: CYBELLE 0.1 MG/0.02 MG FILM KAPLI TABLET, 21 ADET, LEVERETTE 0.15 MG/0.03 MG FILM KAPLI TABLET , 21 TABLETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEnzacamene
go.drugbank.com/drugs/DB11219ApprovedCommonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter.
Mixtures: Outback 2-in-1 Insect Repellent and Protective Sunscreen, Anthelios S - Ecran Solaire SPF 30Synonyms: 3-(4-methylbenzylidene)camphor, 4-MBCFlorbetapir F-18
go.drugbank.com/drugs/DB09149ApprovedInvestigationalFlorbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide … that plays a key role in Alzheimer's Disease pathogenesis.
Synonyms: 4-{(E)-2-[6-(2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl}-N-methylaniline, Florbetapir F-18Berotralstat
go.drugbank.com/drugs/DB15982ApprovedInvestigational[A225106] Berotralstat was first approved by the FDA on December 3, 2020, as the first once-daily oral therapy to prevent angioedema attacks of HAE in adults and pediatric patients 12 years and older. … [L41960] In December 2025, the FDA expanded Berotralstat pediatric use with approval of an oral pellet formulation for prophylaxis in children with HAE aged 2 and older.[L54793,L54798]
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide, (+)-1-(3-(aminomethyl) phenyl)-N-(5-((3-cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide dihydrochlorideGliclazide
go.drugbank.com/drugs/DB01120ApprovedInvestigationala sulfonamide group able to release a proton and the presence of one aromatic group. … [A39546] On the other hand, based on the pharmacological efficacy, gliclazide is considered a second-generation sulfonylurea which presents a higher potency and a shorter half-life.
Mixtures: DUODİA 80 MG/500 MG TABLET, 30 ADET, GLIFOR PLUS 30 MG/1000 MG DEĞIŞTIRILMIŞ SALIMLI TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSulindac
go.drugbank.com/drugs/DB00605ApprovedInvestigationalThere is evidence from some studies that sulindac may be associated with fewer gastrointestinal side effects than other NSAIDs, except for the cyclooxygenase-2 (COX-2) inhibitor drug class. … While its full mechanism of action is not fully understood, sulindac is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and COX-2.
Categories: Non COX-2 selective NSAIDSSynonyms: cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid, (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acidOlmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigationalOlmesartan is commonly used for the management of hypertension and Type 2 Diabetes-associated nephropathy, particularly in patients who are unable to tolerate ACE inhibitors. … ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis
Mixtures: OLMECOMB PLUS 40 MG/5 MG/25 MG FILM KAPLI TABLET, 30 ADET, OLMECOMB PLUS 20 MG/5 MG/12,5 MG FİLM KAPLI TABLET, 30 ADETCategories: Angiotensin 2 Receptor Blocker