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Displaying results 3291 - 3300 of 10000 in total
  1. Drug

    PLX51107

    go.drugbank.com/drugs/DB17543
    Investigational

    PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family. … [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin-3-yl)-
  2. Drug

    OXI-4503

    go.drugbank.com/drugs/DB05143
    Investigational

    OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). … Preclinical studies have demonstrated that OXI-4503 has (i) single-agent activity against a range of xenograft tumor models; and (ii) synergistic or additive effects when incorporated in various combination

    Synonyms: Combretastatin A-1 bis(phosphate), Combretastatin A1 diphosphate
  3. Drug

    Ketoprofen

    go.drugbank.com/drugs/DB01009
    ApprovedInvestigationalVet approved

    Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

    Synonyms: m-Benzoylhydratropic acid, 2-(3-Benzoylphenyl)propionic acidInternational brands: Orudis KT
  4. Drug

    Caricotamide

    go.drugbank.com/drugs/DB18950
    Investigational

    Caricotamide is under investigation in clinical trial NCT00746590 (Study of Anti-tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma).

    Synonyms: 1-(2-amino-2-oxoethyl)-1,4-dihydropyridine-3-carboxamide
  5. Drug

    PXS-5505

    go.drugbank.com/drugs/DB17510
    Investigational

    Synonyms: 2-buten-1-amine, 3-fluoro-4-(8-quinolinylsulfonyl)-, (2z)-
  6. Drug

    Timepidium

    go.drugbank.com/drugs/DB13850
    Investigational

    Synonyms: 3-(di-2-thienylmethylene)-5-methoxy-1,1-dimethyl-piperidiniumCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    (S)-5-(7-(4-(4-Ethyl-4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methylisoxazole

    go.drugbank.com/drugs/DB08725
    Experimental

    (S)-5-(7-(4-(4-Ethyl-4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methylisoxazole is a solid. This compound belongs to the phenol ethers. … These are aromatic compounds containing an ether group substituted with a benzene ring. This substance targets the protein genome polyprotein.

    Synonyms: (S)-5-(7-(4-(4-Ethyl-4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methylisoxazole
  8. Drug

    Depulfavirine

    go.drugbank.com/drugs/DB18890
    Investigational

    Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).

    Synonyms: 2-[4-Bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide, Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-
  9. Drug

    NP-51

    go.drugbank.com/drugs/DB16995
    Investigational

    Synonyms: 3-pyridinecarboximidamide, n-(2-hydroxy-3-(1-piperidinyl)propoxy)-, (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoximeSalts: BGP-15
  10. Drug

    IM-156 free base

    go.drugbank.com/drugs/DB17121
    Investigational

    Synonyms: 1-pyrrolidinecarboximidamide, n-(imino((4-(trifluoromethoxy)phenyl)amino)methyl)-, 1-Pyrrolidinecarboximidamide, N-[imino[[4-(trifluoromethoxy)phenyl]amino]methyl]-Categories: Heterocyclic Compounds, 1-Ring