NP-51
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- NP-51
- DrugBank Accession Number
- DB16995
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 278.356
Monoisotopic: 278.174275964 - Chemical Formula
- C14H22N4O2
- Synonyms
- (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime
- 3-pyridinecarboximidamide, n-(2-hydroxy-3-(1-piperidinyl)propoxy)-
- Bgp-15 free base
- External IDs
- NP-51
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key BGP-15 RLN2GTG4YS 66611-37-8 ISGGVCWFTPTHIX-UHFFFAOYSA-N
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 28ENT76V8K
- CAS number
- 66611-38-9
- InChI Key
- MVLOQULXIYSERZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H22N4O2/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18/h4-6,9,13,19H,1-3,7-8,10-11H2,(H2,15,17)
- IUPAC Name
- N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidamide
- SMILES
- OC(CONC(=N)C1=CC=CN=C1)CN1CCCCC1
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0249173
- ChemSpider
- 7992854
- ChEMBL
- CHEMBL4747845
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Terminated Treatment Diabetes Mellitus 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.58 mg/mL ALOGPS logP 0.35 ALOGPS logP 0.35 Chemaxon logS -2.7 ALOGPS pKa (Strongest Acidic) 14.03 Chemaxon pKa (Strongest Basic) 9.21 Chemaxon Physiological Charge 2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 81.47 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 98.44 m3·mol-1 Chemaxon Polarizability 30.14 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 19, 2022 16:38 / Updated at September 28, 2023 05:47