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Displaying results 3301 - 3310 of 3592 in total
  1. Drug

    Picafibrate

    go.drugbank.com/drugs/DB19574
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Picafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

  2. Drug

    Tiafibrate

    go.drugbank.com/drugs/DB19874
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Tiafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

  3. Drug

    Iolopride I-123

    go.drugbank.com/drugs/DB20028
    Experimental

    The usage of the INN stem '-pride' in the name indicates that Iolopride I-123 is a sulpiride derivative and analogue. Iolopride I-123 has a monoisotopic molecular weight of 400.06 Da.

  4. Drug

    Sitofibrate

    go.drugbank.com/drugs/DB21192
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Sitofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

  5. Drug

    Zatonacaftor

    go.drugbank.com/drugs/DB21625
    Experimental

    The usage of the INN stem '-caftor' in the name indicates that Zatonacaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.

  6. Drug

    Ulevostinag

    go.drugbank.com/drugs/DB14721
    Investigational

    Specifically, expression of IFN-beta (IFNb) enhances the cross-presentation of tumor-associated antigens by CD8alpha-positive and CD103-positive dendritic cells (DCs) to cytotoxic T lymphocytes (CTLs).

  7. Drug

    Amifampridine

    go.drugbank.com/drugs/DB11640
    Approved

    Amifampridine phosphate is a more stable salt that serves as an active ingredient of EMA-approved Firdapse, which was previously marketed as Zenas. … In phase III clinical trials of adult patients with LEMS, treatment of amifampridine significantly improved symptoms of LEMS compared to placebo with good tolerance [A33864].

  8. Drug

    Natural Killer Cell

    go.drugbank.com/drugs/DB15721
    Investigational

    It is also possible to culture UCB CD34+ hematopoietic stem cells (HSCs) under stimulation of IL-2, IL-15, and stem cell factor (SCF) in a system to develop NK cells. … Induced pluripotent stem cells (iPSCs) and human embryonic stem cells (HESCs) are also used to generate NK cells through a two-step culture method resulting in CD34+ cells.

  9. Drug

    Placental Mesenchymal Stem Cells

    go.drugbank.com/drugs/DB15730
    Investigational

    It can be obtained relatively easily as medical waste from which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem cells. … The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs).

    Synonyms: Placental Mesenchymal Stem Cells
  10. Drug

    Fluorfenidine F-18

    go.drugbank.com/drugs/DB19557
    Experimental

    The usage of the INN stem '-nidine' in the name indicates that Fluorfenidine F-18 is a a2 adrenoreceptor agonist. Fluorfenidine F-18 has a monoisotopic molecular weight of 382.07 Da.