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CE-224535
go.drugbank.com/drugs/DB12113InvestigationalCE-224535 has been used in trials studying the treatment of Osteoarthritis.
Categories: Heterocyclic Compounds, 1-RingSotatercept
go.drugbank.com/drugs/DB12118ApprovedInvestigationalSotatercept is an activin signalling inhibitor. … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain.
Categories: Immunoglobulin GSynonyms: (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-Entospletinib
go.drugbank.com/drugs/DB12121InvestigationalEntospletinib has been used in trials studying the treatment of Oncology, Follicular Lymphoma, B-cell Malignancies, Mantle Cell Lymphoma, and Non-Hodgkin Lymphoma, among others.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPF-03715455
go.drugbank.com/drugs/DB12138InvestigationalPF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive, and Chronic Obstructive Pulmonary Disease (COPD).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingAlisporivir
go.drugbank.com/drugs/DB12139InvestigationalAlisporivir has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C.
Bucillamine
go.drugbank.com/drugs/DB12160InvestigationalBucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.
Categories: Compounds used in a research, industrial, or household settingPresatovir
go.drugbank.com/drugs/DB12165InvestigationalPresatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTralokinumab
go.drugbank.com/drugs/DB12169ApprovedInvestigationalWhile AD is a heterogenous condition with a variety of apparent genetic and environmental causes,[A242422] it is primarily driven by the pro-inflammatory cytokine interleukin-13 (IL-13). … [A242427] Tralokinumab is a fully human IgG4 monoclonal antibody targeted against IL-13.
Tricaprylin
go.drugbank.com/drugs/DB12176InvestigationalTricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
Categories: Compounds used in a research, industrial, or household settingSecoisolariciresinol
go.drugbank.com/drugs/DB12179InvestigationalSecoisolariciresinol has been used in trials studying the prevention of Breast Cancer.
Categories: P-glycoprotein inhibitors