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PTI-801
go.drugbank.com/drugs/DB05300InvestigationalPTI-801 can minimize the opioid tolerance, dependence or addiction that is often associated with repeat use of oxycodone. … It is a combination of oxycodone with ultralow-dose naltrexone, an opioid antagonist.
Benzgalantamine
go.drugbank.com/drugs/DB19353ApprovedInvestigational[L51564] Benzgalantamine was approved by the FDA in July 2024 for the treatment of mild-to-moderate dementia in Alzheimer's patients.[L51534,L51564]
Pagoclone
go.drugbank.com/drugs/DB04903InvestigationalIt is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures … Pagoclone is an anxiolytic drug from the cyclopyrrolone family, which is related to other more well known drugs such as the sleeping medication zopiclone.
2G7
go.drugbank.com/drugs/DB18589Experimental2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Dipivefrin
go.drugbank.com/drugs/DB00449ApprovedWithdrawnDipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Elsulfavirine
go.drugbank.com/drugs/DB14929InvestigationalElsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food
Amrinone
go.drugbank.com/drugs/DB01427ApprovedWithdrawnAmrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Iohexol
go.drugbank.com/drugs/DB01362ApprovedInvestigationalIohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Enoximone
go.drugbank.com/drugs/DB04880ApprovedInvestigationalWithdrawnTrials were halted in the U.S., but the drug is used in various countries.
Furosemide
go.drugbank.com/drugs/DB00695ApprovedInvestigationalVet approvedIt is an anthranilic acid derivative. … [L7961] It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body.