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Interferon alfacon-1
go.drugbank.com/drugs/DB00069ApprovedWithdrawnInterferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of the amino acid positions. … Prior to final purification, Interferon alfacon-1 is allowed to oxidize to its native state, and its final purity is achieved by sequential passage over a series of chromatography columns.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsThyroglobulin
go.drugbank.com/drugs/DB01584ApprovedWithdrawnThe active form of thyroxine, triiodothyronine, is produced both within the thyroid gland and periphery by 5'-deiodinase. … Thyroglobulin (also known as Tg) is an enzyme thyroid hormone used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3).
Categories: Amino Acids, Peptides, and ProteinsTriflusal
go.drugbank.com/drugs/DB08814ApprovedWithdrawnTriflusal is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative. … Uriach and Company and even though it is commercialized in different countries it is not approved by the FDA, EMA or HealthCanada.
Categories: Blood and Blood Forming OrgansAllogeneic processed thymus tissue
go.drugbank.com/drugs/DB16736Approved[L38929] Congenital athymia is a rare condition that leads to the absence of a thymus at birth and a high premature mortality rate, with patients typically dying by age two or three. … As part of the immune system, the thymus is an organ responsible for the maturation and selection of T cells [A239814]; thus, patients without a functional thymus experience profound immunodeficiency and
Tirzepatide
go.drugbank.com/drugs/DB15171ApprovedInvestigational[A246265] Tirzepatide was approved by the FDA on May 13, 2022, under the brand name MOUNJARO by the FDA for the treatment of adults with type 2 diabetes, making it the first and only GIP and GLP-1 receptor … agonists in preclinical and clinical trials.
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsMetallo-beta-lactamase type 2
go.drugbank.com/bio_entities/BE0001212TargetEnzymeBacteroides fragilisConfers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
Synonyms: Carbapenem and cephamycin resistanceParaldehyde
go.drugbank.com/drugs/DB09117ApprovedWithdrawnParaldehyde is used as an ingredient in some cough medicines as an expectorant, but its efficacy for this indication has not been confirmed and its use as an expectorant may possibly be due to a placebo … It is classified as a central nervous system (CNS) depressant and has also been found to be an effective anticonvulsant, hypnotic and sedative agent due to its CNS depressant properties.
Categories: Hypnotics and SedativesrCFP-10
go.drugbank.com/drugs/DB21907ApprovedrCFP-10 is a recombinant culture filtrate protein of _Mycobacterium tuberculosis_ used as an ingredient in the diagnostic agent SIILTIBCY along with [rdESAT-6].[L53638]
Obstructive Sleep Apnea (OSA)
go.drugbank.com/conditions/DBCOND0040865Drugs: ModafinilSynonyms: Obstructive Sleep Apnea Syndrome andHomatropine methylbromide
go.drugbank.com/drugs/DB00725ApprovedIt may also be used to prevent nausea, vomiting, and motion sickness.
Mixtures: Hydrocodone Bitartrate and Homatropine Methylbromide, Hydrocodone Bitartrate and Homatropine MethylbromideCategories: Alimentary Tract and Metabolism, Belladonna and Derivatives, Plain