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Displaying results 3341 - 3350 of 10000 in total
  1. Drug

    KW-7158

    go.drugbank.com/drugs/DB05498
    Experimental

    KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity … The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root ganglion

  2. Drug

    Osemozotan

    go.drugbank.com/drugs/DB05339
    Experimental

    MN-305 is a novel, potent and highly selective serotonin 5-HT1A receptor agonist under development by MediciNova for the treatment of anxiety disorders beginning with Generalized Anxiety Disorder (GAD)

  3. Drug

    Garden snail mucin

    go.drugbank.com/drugs/DB14244
    Investigational

    Garden snail mucin is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

  4. Drug

    Argan oil

    go.drugbank.com/drugs/DB14310
    Investigational

    Argan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  5. Drug

    Macadamia oil

    go.drugbank.com/drugs/DB14330
    Investigational

    Macadamia oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  6. Drug

    Tribulus terrestris

    go.drugbank.com/drugs/DB14358
    Investigational

    Tribulus terrestris is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  7. Drug

    Mevastatin

    go.drugbank.com/drugs/DB06693
    Experimental

    During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels. … Mevastatin is a pro-drug that is activated by <i>in vivo</i> hydrolysis of the lactone ring. It has served as one of the lead compounds for the development of the synthetic compounds used today.

  8. Drug

    Edetate calcium disodium anhydrous

    go.drugbank.com/drugs/DB14598
    ApprovedInvestigational

    Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted F...

  9. Drug

    Fimasartan

    go.drugbank.com/drugs/DB09279
    Investigational

    Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand name _Kanarb_ by Boryung Pharmaceuticals. … It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials.

  10. Drug

    Bivalirudin

    go.drugbank.com/drugs/DB00006
    ApprovedInvestigational

    Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is a...