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Displaying results 3381 - 3390 of 9886 in total
  1. Drug

    Rolusafine

    go.drugbank.com/drugs/DB21617
    Experimental

    Rolusafine has a monoisotopic molecular weight of 306.14 Da. … Rolusafine is a small molecule drug. The usage of the INN stem '-afine' in the name indicates that Rolusafine is a antifungal squalene mono-oxygenase inhibitor.

  2. Drug

    Merigolix

    go.drugbank.com/drugs/DB21628
    Experimental

    Merigolix has a monoisotopic molecular weight of 752.24 Da. … Merigolix is a small molecule drug. The usage of the INN stem '-golix' in the name indicates that Merigolix is a gonadotropin releasing hormone (GnRH) antagonist.

  3. Drug

    Lerzeparib

    go.drugbank.com/drugs/DB21650
    Experimental

    Lerzeparib has a monoisotopic molecular weight of 365.15 Da. … Lerzeparib is a small molecule drug. The usage of the INN stem '-parib' in the name indicates that Lerzeparib is a poly-ADP-Ribose polymerase inhibitor.

  4. Drug

    Nurandociguat

    go.drugbank.com/drugs/DB21720
    Investigational

    Nurandociguat has a monoisotopic molecular weight of 571.25 Da. … Nurandociguat is a small molecule drug. The usage of the INN stem '-ciguat' in the name indicates that Nurandociguat is a guanylate cyclase activator and stimulator.

  5. Drug

    Phenoxymethylpenicillin

    go.drugbank.com/drugs/DB00417
    ApprovedInvestigationalVet approved

    Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK.[A178609] It is a phenoxymethyl analog of Penicillin G, or [benzylpenicillin].

    Products: Nu-pen-VK Tablets 300mg, PEN MEGA 1A PHARMA
  6. Drug

    Remdesivir

    go.drugbank.com/drugs/DB14761
    ApprovedInvestigational

    [A222398] Remdesivir (GS-5734) is an adenosine triphosphate analogue first described in the literature in 2016 as a potential treatment for Ebola. … Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia

  7. Drug

    Pemigatinib

    go.drugbank.com/drugs/DB15102
    ApprovedInvestigational

    Pemigatinib is a small molecule kinase inhibitor with antitumour activity. … [A193719] FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide variety of cancers including those of the urinary bladder, breast

  8. Drug

    Brexucabtagene autoleucel

    go.drugbank.com/drugs/DB15699
    ApprovedInvestigational

    Mantle cell lymphoma (MCL) is a heterogeneous sub-category of non-Hodgkin's lymphoma that can be classified as either an aggressive nodal or an indolent leukemic non-nodal variant. … [A216153, A216158] More recently, chimeric antigen receptor (CAR) T cell therapies have been developed that modify a patient's own T cells using viral transduction to bind to and destroy cancerous cells

  9. Drug

    Duvelisib

    go.drugbank.com/drugs/DB11952
    ApprovedInvestigational

    can produce a broad adaptative and innate immune cell inhibitory activity. … All the work around duvelisib showed that this agent is a potent inhibitor of both forms.[A39025] Duvelisib was developed by Verastem, Inc and FDA approved on September 24, 2018.[L4585]

  10. Drug

    Casdatifan

    go.drugbank.com/drugs/DB21701
    Investigational

    Casdatifan has a monoisotopic molecular weight of 439.09 Da. … Casdatifan is a small molecule drug. The usage of the INN stem '-tifan' in the name indicates that Casdatifan is a hypoxia inducible factor (HIF)-2alpha (HIF-2a) inhibitor.