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Displaying results 331 - 340 of 9431 in total
  1. Drug

    Memantine

    go.drugbank.com/drugs/DB01043
    ApprovedInvestigational

    Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … In 2013, this number increased to 44 million. Almost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and to 115 million by 2050 [F4366].

    Categories: NMDA Receptor Antagonists, N-methyl-D-aspartate Receptor Antagonist
  2. Drug

    Mirvetuximab

    go.drugbank.com/drugs/DB16235
    Investigational

    Synonyms: Immunoglobulin g1, anti-(human folate receptor .alpha.) (human-mus musculus monoclonal m9346a heavy chain), disulfide with human-mus musculus monoclonal m9346a light chain, dimer
  3. Drug

    Glycol salicylate

    go.drugbank.com/drugs/DB11323
    Approved

    This drug belongs to the _salicylate_ group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain [L2691]. … Glycol salicylate, also known as _2-hydroxyethyl salicylate_, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol.

    Mixtures: Nopen Hot, Salonpas 30 Hot
  4. Drug

    Lonigutamab

    go.drugbank.com/drugs/DB18940
    Investigational

    Lonigutamab is under investigation in clinical trial NCT05683496 (Efficacy and Safety of Lonigutamab in Subjects With Thyroid Eye Disease (TED)).

    Synonyms: Immunoglobulin g1 (de-c-terminal-lysine), anti-(human insulin-like growth factor i receptor) (human-mus musculus monoclonal hz208f2-4 .gamma.1-chain), disulfide with human-mus musculus monoclonal hz208f2, Immunoglobulin g1-kappa, anti-(homo sapiens igf1r (insulin like growth factor 1 receptor, igf1-r, igf-1r, cd221)), humanized monoclonal antibody
  5. Drug

    KITE-222

    go.drugbank.com/drugs/DB17195
    Investigational

    Synonyms: An autologous chimeric antigen receptor (CAR) T-cell therapy engineered to express an antibody-derived single-chain variable fragment that recognizes C-type lectin-like molecule-1 (CLL-1)
  6. Drug

    Pabinafusp alfa

    go.drugbank.com/drugs/DB15633
    Investigational

    Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).

    Synonyms: Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase, glycoform alfa:, IMMUNOGLOBULIN G1, ANTI-(HUMAN TRANSFERRIN RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JR-141 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN IDURONATE
  7. Drug

    Acyclovir

    go.drugbank.com/drugs/DB00787
    ApprovedInvestigational

    Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis. … [L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old.

    Products: AVIREX-T, ACYCLIN S/CREMA TB X 5 Y 15 G
  8. Drug

    Lumiliximab

    go.drugbank.com/drugs/DB06162
    Investigational

    Results published from the CLL clinical trial failed to meet primary endpoints. … It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE antibody, for the potential treatment of allergic conditions.

    Synonyms: IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA.-CHAIN, DIMER, IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .GAMMA.1-CHAIN), DISULPHIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA.-CHAIN, DIMER
  9. Drug

    AOC-1020

    go.drugbank.com/drugs/DB18621
    Investigational

    AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded

    Synonyms: An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide
  10. Drug

    Butabarbital

    go.drugbank.com/drugs/DB00237
    ApprovedIllicitWithdrawn

    [A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. … Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.