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Displaying results 3401 - 3410 of 3481 in total
  1. Drug

    p-Quaterphenyl

    go.drugbank.com/drugs/DB12794
    Investigational

    p-Quaterphenyl has been used in trials studying the treatment of Malaria.

  2. Drug

    Laniquidar

    go.drugbank.com/drugs/DB12799
    Investigational

    Laniquidar has been used in trials studying the treatment of Breast Cancer.

    Categories: P-glycoprotein inhibitors
  3. Drug

    Trifarotene

    go.drugbank.com/drugs/DB12808
    ApprovedInvestigational

    Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to vitamin ...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  4. Drug

    Cepeginterferon alfa-2B

    go.drugbank.com/drugs/DB12814
    Investigational

    Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  5. Drug

    Tandospirone

    go.drugbank.com/drugs/DB12833
    Investigational

    Tandospirone has been used in trials studying the treatment of Schizophrenia.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Fenobam

    go.drugbank.com/drugs/DB12931
    Investigational

    in clinical trial NCT00637221 (Open Label Study Investigating Safety and Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance Tasks, Adults With Fragile X

  7. Drug

    Dihydralazine

    go.drugbank.com/drugs/DB12945
    ApprovedWithdrawn

    Dihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  8. Drug

    Pexidartinib

    go.drugbank.com/drugs/DB12978
    ApprovedInvestigational

    Pexidartinib is a selective tyrosine kinase inhibitor that works by inhibiting the colony-stimulating factor (CSF1)/CSF1 receptor pathway. Pexidartinib was originally developed by Daiichi Sankyo, Inc. and it was approved by the FDA in Au...

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Substrates
  9. Drug

    Nepicastat

    go.drugbank.com/drugs/DB12979
    Investigational

    Nepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.

    Synonyms: (S)-5-aminomethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1,3-dihydroimidazole-2-thioneCategories: P-glycoprotein substrates
  10. Drug

    Mephedrone

    go.drugbank.com/drugs/DB13108
    Investigational

    Mephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates