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Displaying results 3401 - 3410 of 10000 in total
  1. Drug

    Mavorixafor

    go.drugbank.com/drugs/DB05501
    ApprovedInvestigational

    [L50647] WHIM syndrome is caused by mutations in the _CXCR4_ gene, which leads to overactivation of CXCR4 signalling pathways.[A263652] Mavorixafor prevents the activation of CXCR4. … [L50642] It was first approved by the FDA on April 30, 2024, for the treatment of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome, a genetic immunodeficiency disorder characterized

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Substrates
  2. Drug

    MK-1496

    go.drugbank.com/drugs/DB12763
    Investigational

    MK-1496 has been used in trials studying the treatment of Neoplasms and Malignant.

  3. Drug

    MK-5108

    go.drugbank.com/drugs/DB12556
    Investigational

    MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors.

  4. Drug

    Modakafusp alfa

    go.drugbank.com/drugs/DB16399
    Investigational

    Multiple Myeloma (MM)). … Modakafusp alfa is under investigation in clinical trial NCT03215030 (A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-573 in Participants With Refractory

  5. Indication

    Human papillomavirus type 16

    go.drugbank.com/conditions/DBCOND0093637
    Drugs: Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen
    Synonyms: HPV-16, Human Papillomavirus 16
  6. Drug

    Vanadium

    go.drugbank.com/drugs/DB13971
    Approved

    Mixtures: Protect Plus SO 60, Men's 50+
  7. Drug

    MM-111

    go.drugbank.com/drugs/DB17983
    Investigational

    MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.

  8. Drug

    Lutein

    go.drugbank.com/drugs/DB00137
    ApprovedNutraceutical

    In green plants, xanthophylls act to modulate light energy and serve as non-photochemical quenching agents to deal with triplet chlorophyll (an excited form of chlorophyll), which is overproduced at very … Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids.

  9. Drug

    Ordesekimab

    go.drugbank.com/drugs/DB16649
    Investigational

    Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease).

  10. Drug

    GC012F

    go.drugbank.com/drugs/DB22406
    Investigational

    GC012F is under investigation in clinical trial NCT06419166 (An Exploratory Clinical Study of GC012F Injection for Refractory gMG).