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Ethinylestradiol
go.drugbank.com/drugs/DB00977ApprovedInvestigational[A191107] Ethinylestradiol was granted FDA approval on 25 June 1943.[L11884] … [A191107] These properties were achieved by the substitution of an ethinyl group at carbon 17 of [estradiol].[A191107] Ethinylestradiol soon replaced [mestranol] in contraceptive pills.
Mixtures: VERONIQ ® 3 MG / 30 MCG, Necon 10/11Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesClevidipine
go.drugbank.com/drugs/DB04920ApprovedInvestigationalClevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Categories: Heterocyclic Compounds, 1-Ring, Calcium-Regulating Hormones and AgentsProducts: Cleviprex 0,5 mg/ml Emulsion zur InjektionOrphenadrine
go.drugbank.com/drugs/DB01173ApprovedInvestigationalA muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Synonyms: N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]ethylamine, N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamineMixtures: Norgesic 35 mg/450 mg Tabletten, MYOGESIC-GTozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigationalComirnaty is also approved for use as a fourth booster shot in adults 50 years of age and older.[L41350] … [L15027] On December 11, 2020, the FDA issued an Emergency Use Authorization (EUA) based on 95% efficacy in clinical trials and a similar safety profile to other viral vaccines over a span of approximately
Synonyms: Pfizer-BioNTech COVID-19 VaccineMixtures: Comirnaty Original & Omicron Ba.4/ba.5, Comirnaty Original & Omicron Ba.4/ba.5Naltrexone
go.drugbank.com/drugs/DB00704ApprovedInvestigationalVet approvedIt is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. … Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone.
Mixtures: Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-ReleaseCategories: Heterocyclic Compounds with 4 or More Rings, Alimentary Tract and MetabolismCocaine
go.drugbank.com/drugs/DB00907ApprovedIllicitInvestigationalIt is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. … It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse.
Categories: Analgesics and Anesthetics, Cytochrome P-450 SubstratesSynonyms: methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl esterMagnesium cation
go.drugbank.com/drugs/DB01378ApprovedInvestigationalNutraceuticalWithdrawnMagnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. … When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend
Synonyms: Magnesium, ion(Mg2+)Mixtures: MAGVEL 365 MG GRANÜL İÇEREN SAŞE, 10 ADET, KALSİMAG-D3 1000 MG/300 MG/880 IU EFERVESAN GRANÜL, 30 ADETDiosmin
go.drugbank.com/drugs/DB08995ApprovedInvestigationalDiosmin is widely available over-the-counter and demonstrates a favourable a favorable safety profile.[A232890,T840,L33040] … Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease.
Synonyms: 3',5,7-trihydroxy-4'-methoxyflavone 7-rhamnoglucoside, 3',5,7-trihydroxy-4'-methoxyflavone-7-rutinosideMixtures: DIOKERN 450 MG/50 MG FILM KAPLI TABLET,30 ADET, DIOKERN 450 MG/50 MG FILM KAPLI TABLET,60 ADETInvasive Infection caused by Streptococcus pneumoniae serotype 5
go.drugbank.com/conditions/DBCOND0093623Drugs: Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigenSynonyms: Invasive Infection caused by Streptococcus pneumoniae serotype 5Exemestane
go.drugbank.com/drugs/DB00990ApprovedInvestigationalExemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 6-methyleneandrosta-1,4-diene-3,17-dione