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Ferumoxides
go.drugbank.com/drugs/DB09508ApprovedCategories: Compounds used in a research, industrial, or household settingNeratinib
go.drugbank.com/drugs/DB11828ApprovedInvestigationalNeratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. … Approval was granted to Puma Biotechnology Inc. for the tradename Nerlynx. Neratinib is currently under investigation for use in many other forms of cancer.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexCreatine
go.drugbank.com/drugs/DB00148ApprovedInvestigationalNutraceuticalAn amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Synonyms: N-methyl-N-guanylglycine, N-carbamimidoyl-N-methylglycineAmodiaquine
go.drugbank.com/drugs/DB00613ApprovedInvestigationalA 4-aminoquinoquinoline compound with anti-inflammatory properties.
Nafamostat
go.drugbank.com/drugs/DB12598InvestigationalNafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. … It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome.
Famciclovir
go.drugbank.com/drugs/DB00426ApprovedInvestigationalFamciclovir is a prodrug of penciclovir with higher oral bioavailability. … Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles).
International brands: Wan QiMogamulizumab
go.drugbank.com/drugs/DB12498ApprovedInvestigational[L4168] It was approved for the same indications in Canada in June 2022. … Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4) for the treatment of Mycosis Fungoides (MF) and Sézary Syndrome (SS), the most common subtypes of
Fezolinetant
go.drugbank.com/drugs/DB15669ApprovedInvestigational[A259606] Estrogen is a potent neuromodulator, particularly in the hypothalamus, and has been shown to be involved as a negative regulator in generating Gonadotropin-releasing hormone (GnRH) pulse through … [A259591,A259596] Although mostly considered a nuisance, vasomotor symptoms can significantly affect quality of life, as women with 7 or more moderate to severe VMS daily have reported a decline in sleep
Beractant
go.drugbank.com/drugs/DB06761ApprovedBeractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. … Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as
Daclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnin de novo allogeneic renal transplantation and used concomitantly with an immunosuppressive regimen like cyclosporine and corticosteroids in patients who are not hight immunized, for commercial reasons … Daclizumab is a composite of human (90%) and murine (10%) antibody sequences.