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Darolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigational[A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by the FDA on July 30th, 2019.[L10887] … The goal of treatment with darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and life expectancy for those with advanced prostate cancer.
Categories: Antineoplastic and Immunomodulating Agents, Hormone Antagonists and Related AgentsSibeprenlimab
go.drugbank.com/drugs/DB18919ApprovedInvestigational[L54633] APRIL is a member of the tumour necrosis factor superfamily that regulates and modulates activated B cells. … [A274853, A274858] Sibeprenlimab is a humanized immunoglobulin G2 (IgG2) monoclonal antibody produced by Chinese Hamster Ovary (CHO) cells.
Categories: Amino Acids, Peptides, and ProteinsAcetic acid
go.drugbank.com/drugs/DB03166ApprovedInvestigational(Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus. … Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent.
Mixtures: Hydrocortisone and Acetic Acid, Hydrocortisone and Acetic AcidCategories: Indicators and Reagents, Genito Urinary System and Sex HormonesTofersen
go.drugbank.com/drugs/DB14782ApprovedInvestigational[A259028,A259033] Tofersen was granted accelerated approval from the FDA on April 25, 2023, as the first treatment for adults with ALS caused by SOD1 mutation. … [L46133] Continual FDA approval is contingent on clinical benefits from ongoing trials, particularly the Phase 3 ATLAST study in people with presymptomatic SOD1-ALS.
Categories: Nucleic Acids, Nucleotides, and NucleosidesPhenylacetic acid
go.drugbank.com/drugs/DB09269ApprovedPhenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a disagreeable odor. … Because it is used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries including the United States and China.
Mixtures: Sodium Phenylacetate and Sodium Benzoate, Sodium Phenylacetate and Sodium BenzoateCategories: Alimentary Tract and Metabolism, sodium benzoate and sodium phenylacetateEtizolam
go.drugbank.com/drugs/DB09166InvestigationalIt is not approved for use by FDA in the US; however it remains unscheduled in several states and is legal for research purposes. … Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesPhenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalPhenoxyethanol has been classified as an antimicrobial and preservative by Health Canada [L2623]. … It is produced by reacting phenol (EU) and ethylene oxide (EU) at a high temperature and pressure. This substance occurs naturally in green tea (EU) [L2621].
Mixtures: Hand Sanitizer, Edens Hand Sanitizing WipesDeslanoside
go.drugbank.com/drugs/DB01078ApprovedA cardiotonic glycoside from the leaves of Digitalis lanata.
Crizanlizumab
go.drugbank.com/drugs/DB15271ApprovedInvestigationalSickle cell disease can lead to excruciating pain, stroke, infection, and various other complications arising from the blockage of blood vessels. … [A187907] Crizanlizumab, or SEG101, is given once every 4 weeks and may improve patient adherence. It was developed by Novartis and was granted FDA approval on November 15, 2019.
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsCidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigational[FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223] … Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS.
Categories: Nucleosides and Nucleotides, Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors