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Civorebrutinib
go.drugbank.com/drugs/DB21641ExperimentalCivorebrutinib is a small molecule drug. The usage of the INN stem '-brutinib' in the name indicates that Civorebrutinib is a agammaglobulinaemia tyrosine kinase (Bruton tyrosine kinase) inhibitor.
mRNA-1010
go.drugbank.com/drugs/DB22484Approved[L64058,L64060] It is administered as a single intramuscular dose. … [L64058] Unlike conventional egg- or cell-based inactivated influenza vaccines, mFLUSIVA is built on the mRNA platform and is manufactured without an egg- or cell-based process.
Categories: Complex MixturesProtriptyline
go.drugbank.com/drugs/DB00344ApprovedSee toxicity section below for a complete listing of side effects. Protriptyline may be used for the treatment of depression. … In addition, TCAs down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use.
Pirtobrutinib
go.drugbank.com/drugs/DB17472ApprovedInvestigational[A256758] Unlike BTK covalent inhibitors, such as [ibrutinib], that bind to the cysteine 481 (Cys481) amino acid within the active site of BTK, the inhibitory activity of pirtobrutinib is maintained even … Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine kinase (BTK).
Synonyms: (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1h-pyrazole-4-carboxamide, 5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-((2s)-1,1,1-trifluoropropan-2-yl)-1h-pyrazole-4-carboxamideCefmetazole
go.drugbank.com/drugs/DB00274ApprovedA semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been n...
Synonyms: (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseInsulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalCompared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced with aspartic acid. … Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin, with a goal of avoiding any periods of hypoglycemia.
Mixtures: NOVOMIX 30 FLEXPEN INJECTION 100 u/ml, NOVOMIX 30 FLEXPEN INJECTION 100 u/mlProducts: 100 U/ML, NOVORAPID FLEXPEN INJECTION 100 u/mlSpesolimab
go.drugbank.com/drugs/DB15626ApprovedInvestigationalSpesolimab is an interleukin-36 (IL-36) receptor antagonist. … [A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved
Donanemab
go.drugbank.com/drugs/DB16647ApprovedInvestigationalDonanemab is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against insoluble N-truncated pyroglutamate amyloid beta (Aβ), [L50978] which is found in the brain amyloid plaques that
Stanolone
go.drugbank.com/drugs/DB02901IllicitInvestigationalDihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemOxilofrine
go.drugbank.com/drugs/DB11610ApprovedOxilofrine is used in combination with [DB11609] as an antitussive. It is currently marketed in Canada by Valeant under the tradename Cophylac.