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Cidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigationalCidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] I...
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTripelennamine
go.drugbank.com/drugs/DB00792ApprovedVet approvedA histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various r...
Categories: Antihistamines for Systemic Use, Antihistamines for Topical UseSuzetrigine
go.drugbank.com/drugs/DB18927ApprovedInvestigationalblocker with analgesic properties[A264948] Na<sub>V</sub>1.8 is abundantly expressed in peripheral sensory nerves to play a role in pain signal transmission, making it a desirable therapeutic target for
Hydroxyproline
go.drugbank.com/drugs/DB08847ApprovedTherapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds.
Nicorandil
go.drugbank.com/drugs/DB09220ApprovedInvestigationalWithdrawnIt is often used for patients with angina who remain symptomatic despite optimal treatment with other antianginal drugs [T28].
International brands: Av-Cor, K-CorSAB-185
go.drugbank.com/drugs/DB16491InvestigationalCategories: Experimental Unapproved Treatments for COVID-19Mecasermin
go.drugbank.com/drugs/DB01277ApprovedInvestigationalThe rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1.
Isoconazole
go.drugbank.com/drugs/DB08943ApprovedIsoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseAmdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnAmidinopenicillanic acid derivative with broad spectrum antibacterial action. It is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseINO-4800
go.drugbank.com/drugs/DB15693InvestigationalINO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. … [A214475] A Phase 1 clinical trial for INO-4800 in the U.S. (NCT04336410) was started on April 3, 2020, with an expected completion date of July 2021.
Categories: Experimental Unapproved Treatments for COVID-19