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HLA class I histocompatibility antigen, A alpha chain
go.drugbank.com/bio_entities/BE0003483TargetHumansAntigen-presenting major histocompatibility complex class I (MHCI) molecule. … Can bind different peptides containing allele-specific binding motifs, which are mainly defined by anchor residues at position 2 and 9 (PubMed:7504010, PubMed:9862734).
Polypeptides: HLA class I histocompatibility antigen, A alpha chainSynonyms: MHC class I antigen A*3, HLA class I histocompatibility antigen, A-3 alpha chainMajor histocompatibility complex class I-related protein 1
go.drugbank.com/bio_entities/BE0003573TargetHumansAntigen-presenting molecule specialized in displaying microbial pyrimidine-based metabolites to alpha-beta T cell receptors (TCR) on innate-type mucosal-associated invariant T (MAIT) cells (PubMed:19416870, PubMed:23457030, PubMed:226924...
Polypeptides: Major histocompatibility complex class I-related protein 1Synonyms: MHC class I-related protein 1, Class I histocompatibility antigen-like proteinPentobarbital
go.drugbank.com/drugs/DB00312ApprovedVet approvedA short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. … It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration.
Synonyms: 5-Ethyl-5-(1-methyl-butyl)-pyrimidine-2,4,6-trione, 5-ethyl-5-(1-methylbutyl)barbituric acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersPeppermint oil
go.drugbank.com/drugs/DB11198ApprovedInvestigationalDue to its effectiveness in relaxing GI smooth muscle but ability to induce gastroesophageal reflux, enteric-coated formulations of peppermint oil has been established which bypass the upper GI tract unmetabolized … It is also an active ingredient in topical analgesics for the relief of joint and muscle pain. Peppermint oil can be applied topically to temporarily relieve tension-type headache.
Mixtures: Cal Mo Dol Ont, BUĞUMENTOL BUĞU, 40 GCategories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic ExtractProcainamide
go.drugbank.com/drugs/DB01035ApprovedA derivative of procaine with less CNS action.
Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IaSynonyms: p-Amino-N-(2-diethylaminoethyl)benzamide, p-Aminobenzoic diethylaminoethylamideNYHA Class I or II heart failure
go.drugbank.com/conditions/DBCOND0025082Drugs: CarvedilolSynonyms: NYHA Class I or II heart failureErgocalciferol
go.drugbank.com/drugs/DB00153ApprovedInvestigationalNutraceuticalErgocalciferol is an inactivated vitamin D analog.[A177526] It is synthesized by some plants in the presence of UVB light. … [A177637] The first approved product containing ergocalciferol under the FDA records was developed by US Pharm Holdings and was FDA approved in 1941.[L6058]
Mixtures: Cal/mag 2:1 With D, L-SOLUVIT NCategories: Vitamin D and AnaloguesHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approvedHydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. … [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Synonyms: Kendall's compound F, Reichstein's substance MInternational brands: Polcort H, Preparation H Hydrocortisone CreamPenciclovir
go.drugbank.com/drugs/DB00299ApprovedDisplaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. … Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine, 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine