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Pancrelipase
go.drugbank.com/drugs/DB00085ApprovedInvestigationalPancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase mixture was developed by Ortho-McNeil-J...
International brands: Ku-ZymeMixtures: Alka-pan TabletsVedolizumab
go.drugbank.com/drugs/DB09033ApprovedInvestigationalVedolizumab is a recombinant humanized IgG1 monoclonal antibody directed against the human lymphocyte α4β7 integrin, a key mediator of gastrointestinal inflammation implicated in diseases like ulcerative colitis or Crohn's disease. α4β7 ...
Products: ENTYVIO POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 300MG/VIALTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigationalDue to its SNRI activity, tramadol also has anxiolytic, antidepressant, and anti-shivering effects which are all frequently found as comorbidities with pain. … Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain.
Mixtures: DUODUET - PT, AUROMYOTRAM-P ® TABLETASCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigationalBrimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. … [A178945] Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or at high risk for, cardiopulmonary disease.
Mixtures: Brim-Dor PF, Tim-Brim-Dor PFProducts: TARTRATO DE BRIMONIDINA0.2 %, BRIMOLAG® TARTRATO DE BRIMONIDINA 2MG/ML SOLUCION OFTALMICA.Norethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigationalL9527,L10301,L10304,L10307] First derived in 1951 in Mexico City, norethisterone was originally intended for use as a remedy for irregular menstruation and endometriosis, and was not marketed for use as an
Mixtures: Estradiol / Norethindrone Acetate, Norethindrone and ethinyl estradiolCategories: elagolix, estradiol and norethisterone, relugolix, estradiol and norethisteroneTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigationalTimolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. … [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension.
Mixtures: Van-dorzolamide-timolol, Ag-dorzolamide TimololCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesImipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalThey contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesInternational brands: Depsonil-PMDienogest
go.drugbank.com/drugs/DB09123ApprovedInvestigationalDienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. … In Europe, Australia, Malaysia, Singapore and Japan, dienogest single therapy is an approved treatment for endometriosis to alleviate painful symptoms of endometriosis and reduce endometriotic lesions
Mixtures: Estradiol Valerate and Estradiol Valerate/Dienogest, Estradiol Valerate and Estradiol Valerate/DienogestCategories: dienogest and estradiol, Cytochrome P-450 SubstratesSulodexide
go.drugbank.com/drugs/DB06271ApprovedInvestigationalWithdrawnSulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).
Products: VESSEL DUE F, VESSEL DUE F 250 LSU CAPSULE