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Displaying results 341 - 350 of 9617 in total
  1. Drug

    Albendazole

    go.drugbank.com/drugs/DB00518
    ApprovedInvestigationalVet approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

    Products: DENZOL 20mg/ml Suspension, ZENTEL SUSPENSION 400MG/10ML
  2. Drug

    Afatinib

    go.drugbank.com/drugs/DB08916
    ApprovedInvestigational

    Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. … For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected

    Products: GIOTRIF 20MG FILM-COATED TABLETS, GIOTRIF FILM-COATED TABLETS 20MG
  3. Drug

    Terbinafine

    go.drugbank.com/drugs/DB00857
    ApprovedInvestigationalVet approved

    [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. … [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.[L9064]

    Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineProducts: DERMAFIN CREAM 10MG/G, TEFIN Terbinafine HCl Spray 10mg/g
  4. Drug

    Nalmefene

    go.drugbank.com/drugs/DB06230
    ApprovedInvestigationalWithdrawn

    [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. … [L1024] Nalmefene was approved in the United States in 1995 as an antidote for opioid overdose.[A245839] Nalmefene injection is used to manage known or suspected opioid overdose.

    Products: SELINCRO 18MG FILM KAPLI TABLET ,42 TABLET, SELINCRO 18MG FILM KAPLI TABLET ,7 TABLET
  5. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    Although it is principally believed that guaifenesin elicits an action to facilitate productive cough to manage chest congestion [A177661, L6100, F4516, F4522, F4525], it is not known whether the agent … as an NMDA receptor antagonist [A177652].

    Mixtures: Acetaminophen 500mg, Dextromethorphan HBr 10mg, Guaifenesin 200mg, Phenylephrine HCl 5mg, Entex PACProducts: GUAFENSIN SYRUP 20MG/ML, Homecare Guafensin Syrup 20mg/ml
  6. Drug

    Hydrocodone

    go.drugbank.com/drugs/DB00956
    ApprovedIllicitInvestigational

    [T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain. … Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by [dextromethorphan] in current cough and cold formulations.

    Mixtures: FEMTAX® 5MG/325MG, Vicodin ESProducts: Robidone Syr 1mg/ml, Robidone 1mg/ml Syr
  7. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … It was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug [L2002].

    Products: VINELBINE INJECTION-10MG/ML, NAVELBINE 10MG,INJECTABLE SOLUTION
  8. Drug

    Cholestyramine

    go.drugbank.com/drugs/DB01432
    ApprovedInvestigational

    Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.

    Products: PMS-cholestyramine Pws 400g/can, ANTILIP GRANULADO EN SACHET
  9. Drug

    Prasugrel

    go.drugbank.com/drugs/DB06209
    ApprovedInvestigational

    As a result, inhibition of ADP-mediated platelet activation and aggregation occurs. … Prasugrel was developed by Daiichi Sankyo Co. and is currently marketed in the United States and Canada in cooperation with Eli Lilly and Company for acute coronary syndromes planned for percutaneous coronary

    Products: EFIENT 10MG, EFIENT 10MG FTA
  10. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine]. … Tramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the

    Mixtures: Pat-tramadol/acet, DICLOFENACO SODICO /TRAMADOL HCL 25 MG/25MG.Products: TRAVEX ONE 400MG, TRAMADOL LIBRAPH RET 50MG