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Trimethaphan
go.drugbank.com/drugs/DB01116ApprovedInvestigationalA nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anesthesia, and to induce hypotension during surgery.
Categories: Heterocyclic Compounds, 1-RingRaxibacumab
go.drugbank.com/drugs/DB08902ApprovedInvestigationalRaxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012. … Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons.
Dydrogesterone
go.drugbank.com/drugs/DB00378ApprovedInvestigationalWithdrawnUnlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation. … A synthetic progestational hormone with no androgenic or estrogenic properties.
Synonyms: delta(6)-Retroprogesterone, 6-Dehydro-retro-progesteroneMixtures: FEMOSTON CONTI 1/5 TABLET, FEMOSTON CONTI 1/5Hexachlorophene
go.drugbank.com/drugs/DB00756ApprovedWithdrawnIt is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797) … A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms.
Synonyms: 2,2'-dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane, bis(2-hydroxy-3,5,6-trichlorophenyl)methaneInternational brands: E-Z scrub, Pre-Op IIFructose
go.drugbank.com/drugs/DB04173ApprovedInvestigationalMixtures: Formula EmCategories: Compounds used in a research, industrial, or household settingAlverine
go.drugbank.com/drugs/DB01616ApprovedInvestigationalWithdrawnAlverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. … It can also be used to help relieve period pain.
Mixtures: METEOSPASMYL® CAPSULAS BLANDAS, METEOSPASMYL® CAPSULAS BLANDASCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT1A Receptor AntagonistsNadofaragene firadenovec
go.drugbank.com/drugs/DB17381ApprovedInvestigationalIt is the first gene therapy approved by the FDA for the treatment of bladder cancer.[L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. … Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b).
Synonyms: RAD-IFN, RAD-IFN-2BLJP 1082
go.drugbank.com/drugs/DB05446ExperimentalThe target of the LJP 1082's clot-promoting antibodies is a small region on a key blood protein called beta 2-glycoprotein I. … LJP 1082 is a Toleragen that is designed to shut down the B cells that produce antibodies to ß2 GP1.
Categories: Compounds used in a research, industrial, or household settingChlorphenesin
go.drugbank.com/drugs/DB00856ApprovedCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 3-(4-chlorophenoxy)-1,2-propanediol, 3-(p-chlorophenoxy)-1,2-propanediolCidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigationalCidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223]
Categories: Heterocyclic Compounds, 1-RingSynonyms: ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid, (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid