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Displaying results 3491 - 3500 of 4359 in total
  1. Drug

    Cilomilast

    go.drugbank.com/drugs/DB03849
    Investigational

    It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. … Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD).

  2. Drug

    Ganulameran

    go.drugbank.com/drugs/DB16442
    Investigational

    As such, BNT162b3 has entered a phase I/II study in early September 2020 (NCT04537949). … Pfizer and BioNTech deemed this compound as promising in preclinical trials and have decided to initiate further testing of it.

  3. Drug

    Etilamfetamine

    go.drugbank.com/drugs/DB13285
    Experimental

    Like other amphetamines, this amphetamine analog was used as an appetite suppressant in the 1950s. … Etilamfetamine is also known as N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 controlled drug.

  4. Drug

    8-azaguanine

    go.drugbank.com/drugs/DB01667
    Experimental

    It functions as an antimetabolite and is easily incorporated into ribonucleic acids.

  5. Drug

    Brenetafusp

    go.drugbank.com/drugs/DB19441
    Investigational

    Brenetafusp is under investigation in clinical trial NCT04262466 (Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors).

    Synonyms: Immunoglobulin, anti-(human CD3 antigen ε-chain) (human-Mus musculus single-chain Fv fragment VL-((GGGGS)4GGGS)-VH) fusion protein with peptide linker (GGGGS) fusion protein with T-cell receptor β chain
  6. Drug

    Rivanicline

    go.drugbank.com/drugs/DB05855
    Experimental

    It has subsequently been developed as a potential anti-inflammatory treatment for ulcerative colitis. … It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8.

  7. Drug

    Follitropin

    go.drugbank.com/drugs/DB00066
    ApprovedInvestigational

    The nomenclature “beta” differentiates it from another recombinant human FSH product that was marketed earlier as follitropin alpha. … Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta

  8. Drug

    Furafylline

    go.drugbank.com/drugs/DB14029
    Experimental

    It was developed on the context of asthma as a long-acting alternative for [theophylline].

  9. Drug

    Modipafant

    go.drugbank.com/drugs/DB16237
    Investigational

    Modipafant is under investigation in clinical trial NCT02569827 (Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore).

  10. Drug

    Demexiptiline

    go.drugbank.com/drugs/DB08998
    Experimental

    It is a tricyclic antidepressant which acts primarily as a norepinephrine reuptake inhibitor.