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MPI-674
go.drugbank.com/drugs/DB05749ExperimentalMPI-674 is an aromatase inhibitor (AI) with a well-established, multi-year chronic safety and tolerability profile.
Levobupivacaine
go.drugbank.com/drugs/DB01002ApprovedInvestigationalWithdrawnLevobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. … general, the majority of potential adverse effects are predominantly associated with inappropriate administration methods that may cause systemic exposure and/or toxicity associated with overexposure to an
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSarracenia Purpurea
go.drugbank.com/drugs/DB13965ApprovedWithdrawnIt was used as an injectable pain reliever and during the 19th century, _Sarracenia purpurea_ was used as a treatment of smallpox [A32509]. … Cytoprotection in an in vitro model of diabetic neuropathy has also been studied. However, the use of Sarracenia Purpurea extracts in the clinical setting are limited.
Products: P-BlocVasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigationalVasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour. Vasopressin is v...
Products: VASOPRESSIN INJECTION USP 20 u/ml, VASOPRESINA INYECTABLE 20 U/ML USPTL-895
go.drugbank.com/drugs/DB16471InvestigationalTL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC50 and a Ki of 1.5 nM and 11.9 nM, respectively.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSqualene
go.drugbank.com/drugs/DB11460ApprovedInvestigationalVet approvedWithdrawnSqualene is investigated as an adjunctive cancer therapy.
Miocamycin
go.drugbank.com/drugs/DB13287Approvedshown to be effective against several gram-positive and gram-negative microbes and may be useful in the treatment of upper and lower respiratory tract infections, and urogenital tract infections or as an
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsAbrocitinib
go.drugbank.com/drugs/DB14973ApprovedInvestigationalAbrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1).
Synonyms: PF-04965842Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsmRNA-1283
go.drugbank.com/drugs/DB22668ApprovedInvestigationalmRNA-1283 is a nucleoside-modified messenger RNA (mRNA) encoding the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein of the SARS-CoV-2 Omicron variant lineage JN.1. It is the primary ingredient in mNEX...