Search

Displaying results 3521 - 3530 of 10000 in total
  1. Drug

    PSN9301

    go.drugbank.com/drugs/DB05001
    Experimental

    PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes. … PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for meal-related dosing.

  2. Drug

    Propyl Gallate

    go.drugbank.com/drugs/DB12450
    Investigational

    Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Lisuride

    go.drugbank.com/drugs/DB00589
    Approved

    An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). … It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).

    Synonyms: N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea
  4. Drug

    Alverine

    go.drugbank.com/drugs/DB01616
    ApprovedInvestigationalWithdrawn

    It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.

    Synonyms: N,N-Bis(3-phenylpropyl)ethylamine, N-Ethyl-N-(3-phenylpropyl)benzenepropanamine
  5. Drug

    Guanoxan

    go.drugbank.com/drugs/DB13211
    Approved

    Guanoxan is an antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage. … Guanoxan was approved in the UK but was withdrawn from the market due to hepatotoxicity.

  6. Drug

    Clobutinol

    go.drugbank.com/drugs/DB09004
    ApprovedWithdrawn

    Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients.

  7. Drug

    Tasosartan

    go.drugbank.com/drugs/DB01349
    Experimental

    Tasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan. It is used to treat patients with essential hypertension.

    Categories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    3,3'-diindolylmethane

    go.drugbank.com/drugs/DB11875
    Investigational

    Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    MK-4721

    go.drugbank.com/drugs/DB05933
    Investigational

    MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients

  10. Drug

    Trifluoperazine

    go.drugbank.com/drugs/DB00831
    Approved

    It is used as an antipsychotic and an antiemetic.