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Pegzilarginase
go.drugbank.com/drugs/DB14780Approved[A275423,L56053] Pegzilarginase-nbln received accelerated approval from the U.S. … Pegzilarginase is a recombinant, cobalt-substituted, and pegylated human arginase 1 enzyme therapy designed to address the underlying metabolic deficit in arginase 1 deficiency (ARG1-D).
Etranacogene dezaparvovec
go.drugbank.com/drugs/DB16791ApprovedInvestigational[L44161] It is additionally notable for its cost per treatment - approximately 3.5 million USD - earning it the title of most expensive drug in the world. … [L44181] Hemophilia B is the second most common type of hemophilia,[L44181] with a prevalence of approximately one in 40,000.
Categories: Complex MixturesEvifacotrep
go.drugbank.com/drugs/DB21510InvestigationalEvifacotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Evifacotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist.
Carafiban
go.drugbank.com/drugs/DB19813ExperimentalCarafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Carafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Licostinel
go.drugbank.com/drugs/DB19864ExperimentalLicostinel is a small molecule drug. The usage of the INN stem '-stinel' in the name indicates that Licostinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist.
Orbofiban
go.drugbank.com/drugs/DB20676ExperimentalOrbofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Orbofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Gantofiban
go.drugbank.com/drugs/DB20951ExperimentalGantofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Gantofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Roxifiban
go.drugbank.com/drugs/DB21089ExperimentalRoxifiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Roxifiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Categories: Platelet Glycoprotein GPIIb-IIIa Complex, antagonists & inhibitorsSibrafiban
go.drugbank.com/drugs/DB21420ExperimentalSibrafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Sibrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Categories: Platelet Glycoprotein GPIIb-IIIa Complex, antagonists & inhibitorsPadoprazan
go.drugbank.com/drugs/DB21689ExperimentalPadoprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Padoprazan is a proton pump inhibitor, not dependent on acid activation.