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Meningococcal polysaccharide vaccine group Y
go.drugbank.com/drugs/DB13888ApprovedInvestigationalIt is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup Y. … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia.
Mixtures: Menveo Powder and Solution for Solution for Injection, NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONDanaparoid
go.drugbank.com/drugs/DB06754ApprovedWithdrawnDanaproid is used in the treatment of heparin-induced thrombocytopenia (HIT) as an off-label indication and prevention of post-operative deep venous thrombosis (DVT). … While it was initially approved by the FDA as Orgaran™, danaparoid was withdrawn by Organon International on August 14, 2002, due to a shortage in drug substance by the manufacturer.
Categories: Heparin and similars, Blood and Blood Forming OrgansDihydroergotamine
go.drugbank.com/drugs/DB00320ApprovedInvestigational[A239569] The recently approved Precision Olfactory Delivery technology developed by Impel Neuropharma technology has correlated with an increase of 3-fold in Cmax and 4-fold in AUC despite the solution … Dihydroergotamine is used as an abortive therapy for migraines.
Categories: Ergot Alkaloids and DerivativesSynonyms: (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraene-4-carboxamideSelpercatinib
go.drugbank.com/drugs/DB15685ApprovedInvestigationalIt is currently marketed under the brand name RETEVMO™ by Loxo Oncology Inc.[L13604] Selpercatinib is also approved by the European Commission. … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and [vandetanib], have shown efficacy in RET-driven cancers, their lack of specificity is generally associated
Categories: Antineoplastic and Immunomodulating AgentsProducts: RETSEVMO ® 40MGCitrus bioflavonoids
go.drugbank.com/drugs/DB14586ApprovedMixtures: Vitamin C Wafers 100mg, KORDEL`S C TIME ACID FREE C 1000MG TABLETLetibotulinumtoxinA
go.drugbank.com/drugs/DB16820Approved[L42335] It was approved for use in the treatment of glabellar lines in Canada in June 2022[L42330,L42335] and in the US in March 2024.[L50291,L50296] … [A249920] It was subsequently approved by the FDA in 1992 for use in aesthetic procedures and has since become one of the most popular cosmetic procedures worldwide.
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsAlverine
go.drugbank.com/drugs/DB01616ApprovedInvestigationalWithdrawnIt can also be used to help relieve period pain. … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions.
Categories: Alimentary Tract and MetabolismSynonyms: N,N-Bis(3-phenylpropyl)ethylamine, N-Ethyl-N-(3-phenylpropyl)benzenepropanamineDiphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalThis medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug Administration (FDA) and the DEA in the United States when used in preparations. … A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine.
Mixtures: Diphenoxylate Hydrochloride and Atropine Sulfate, Diphenoxylate Hcl and Atropine SulfateCategories: Alimentary Tract and MetabolismTabelecleucel
go.drugbank.com/drugs/DB17072ApprovedInvestigationalTabelecleucel is an innovative therapy that uses Epstein-Barr virus (EBV)-specific allogeneic cytotoxic T cells (CTLs). … It is produced by mixing T-cells with B-cells that have been infected with the Epstein-Barr virus (EBV).
Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsMosunetuzumab
go.drugbank.com/drugs/DB15434ApprovedInvestigational[L42230] It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells. … ] and [tisagenlecleucel], it is an “off-the-shelf” alternative, readily available to patients.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents