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Ripasudil
go.drugbank.com/drugs/DB13165InvestigationalRipasudil is a well tolerated medication that is used when other drugs have been proven to be non-effective or cannot be administered. … It was first approved for treatment in Japan in September 2014. This medication is available in the form of a 0.4% eye drop solution under the brand name Glanatec.
Didecyldimethylammonium
go.drugbank.com/drugs/DB04221ApprovedInvestigationalMixtures: Clinicare pro Surface SanitizerGadopiclenol
go.drugbank.com/drugs/DB17084ApprovedInvestigationalThe product label includes a black box warning regarding the increased risk for NSF among patients with impaired elimination of the drugs.[L43817] … Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure.
MBO7133
go.drugbank.com/drugs/DB04999ExperimentalHowever, araC is only slowly converted to araCTP in the liver or in primary liver tumors due to low levels of an enzyme in the liver that is required for the conversion of araC to araCMP, the first step … MB07133 uses our HepDirect technology to target a prodrug form of araCMP specifically to the liver.
Moxisylyte
go.drugbank.com/drugs/DB09205ApprovedMoxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist.
Guanethidine
go.drugbank.com/drugs/DB01170ApprovedWithdrawnAn antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepineph...
Estramustine
go.drugbank.com/drugs/DB01196ApprovedWithdrawnA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
SQ-109
go.drugbank.com/drugs/DB05186InvestigationalSQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB. … Currently in Phase I clinical trials, SQ-109 could replace one or more drugs in the current first-line TB drug regimen, simplify therapy, and shorten the TB treatment regimen.
Brentuximab vedotin
go.drugbank.com/drugs/DB08870ApprovedInvestigationalImportantly, bleomycin - a highly toxic agent - was completely removed from the regimen. This demonstrates meaningful progress in treatment for patients affected by this disease.[L1739] … or progression, systemic anaplastic large cell lymphoma (ALCL) after the failure of other treatment regimens, and primary cutaneous ALCL after failure of other treatment regimens.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ADCETRIS 50 MG (POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION), POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIALInfluenza A virus A/Victoria/361/2011 (H3N2) recombinant hemagglutinin antigen
go.drugbank.com/drugs/DB10774ApprovedInvestigationalWithdrawnInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses.
Synonyms: influenza A virus A/Victoria/361/2011 (H3N2) antigen, Influenza A virus A/Victoria/361/2011 (H3N2) recombinant hemagglutinin antigen