Search

Displaying results 3561 - 3570 of 8196 in total
  1. Drug

    Efalizumab

    go.drugbank.com/drugs/DB00095
    ApprovedWithdrawn

    It was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy (PML).[L43797]

  2. Drug

    Pleconaril

    go.drugbank.com/drugs/DB05105
    Investigational

    Food and Drug Administration (FDA) due to the fact that it has been found to induce CYP3A enzyme activity, therefore increasing the risk for serious drug interactions. … Pleconaril is an antiviral drug from _viral capsid inhibitor_ class, manufactured by _Schering-Plough_ and intended for the prevention of acute asthma exacerbations and common cold symptoms in asthmatic

  3. Drug

    Digoxigenin

    go.drugbank.com/drugs/DB03671
    Experimental

    Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.

    Categories: P-glycoprotein substrates
  4. Drug

    KUR-113

    go.drugbank.com/drugs/DB18413
    Investigational

    KUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone fragment. It is being investigated as a bioactive bone graft substitute.

  5. Target

    Carbonyl reductases (CBRs)

    go.drugbank.com/bio_entities/BE0010129
    EnzymeHumans

    Component of the heterotetramer complex KAR (3-ketoacyl-[acyl carrier protein] reductase or 3-ketoacyl-[ACP] reductase) that forms part of the mitochondrial fatty acid synthase (mtFAS). … Beta-subunit of the KAR heterotetramer complex, responsible for the 3-ketoacyl-ACP reductase activity of the mtFAS, reduces 3-oxoacyl-[ACP] to (3R)-hydroxyacyl-[ACP] in a NADPH-dependent manner with no

    Synonyms: KAR beta subunit
  6. Drug

    Chlormadinone

    go.drugbank.com/drugs/DB13528
    Investigational

    Mixtures: ADELLA MINI TABLETA CON RECUBRIMIENTO DE GELATINA, ADELLA MINI TABLETA CON RECUBRIMIENTO DE GELATINACategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  7. Drug

    Oleoyl-estrone

    go.drugbank.com/drugs/DB04870
    Investigational

    Body protein loss is an unpleasant effect of fat loss by the restriction of calories, and studies show that this drug appears to avoid this effect.

  8. Drug

    Aloe vera leaf

    go.drugbank.com/drugs/DB13906
    ApprovedInvestigational

    Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agr...

    Synonyms: Lu hui ye, Lu hui (aloe vera)
  9. Drug

    MBP134

    go.drugbank.com/drugs/DB18686
    Experimental

    MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. It is under investigation for the treatment of Sudan ebolavirus (SUDV).

  10. Drug

    Beremagene geperpavec

    go.drugbank.com/drugs/DB17831
    ApprovedInvestigational

    Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with ...