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Displaying results 3561 - 3570 of 10000 in total
  1. Drug

    Tropisetron

    go.drugbank.com/drugs/DB11699
    ApprovedInvestigationalWithdrawn

    Tropisetron is an indole derivative with antiemetic activity. … As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting

  2. Drug

    Avacincaptad pegol

    go.drugbank.com/drugs/DB15165
    ApprovedInvestigational

    [L47696] AMD is the leading cause of vision loss in developed countries for people over 50 years old, with a global estimate of 170 million individuals affected. … Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule.

  3. Drug

    Rifapentine

    go.drugbank.com/drugs/DB01201
    ApprovedInvestigational

    Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. … Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.

  4. Drug

    ISS-1018

    go.drugbank.com/drugs/DB05463
    Investigational

    ISS 1018 is currently being investigated in combination with HBsAg vaccine as a prophylactic treatment for to prevent Hepatitis B in adults. … It is also being investigated in combination with rituximab for treatment of b-cell or non-hodgkin's lymphoma.

  5. Drug

    Copper oxodotreotide Cu-64

    go.drugbank.com/drugs/DB15873
    Approved

    [A220348] In a head-to-head trial, the former tracer detected twice as many lesions as the latter.[A220348] … Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over <sup>68</sup>Ga-labeled somatostatin analogs for positron emission tomography (PET).

  6. Drug

    Emeramide

    go.drugbank.com/drugs/DB12192
    Investigational

    Emeramide has been used in trials studying the treatment of Mercury Poisoning.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Etafenone

    go.drugbank.com/drugs/DB13845
    Experimental

    Etafenone is a vasodilator.

    Categories: Vasodilators Used in Cardiac Diseases
  8. Drug

    Molnupiravir

    go.drugbank.com/drugs/DB15661
    Investigational

    COVID-19 in adults. … [A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’-triphosphate form.

  9. Drug

    Trinitrotoluene

    go.drugbank.com/drugs/DB01676
    Experimental

    Trinitrotoluene is an explosive chemical that can cause skin irritation and other toxic consequences.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Imazodan

    go.drugbank.com/drugs/DB20144
    Experimental

    Imazodan is a small molecule drug. The usage of the INN stem '-dan' in the name indicates that Imazodan is a cardiac stimulant, pimobendan derivative.

    Categories: Compounds used in a research, industrial, or household setting