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Domiphen
go.drugbank.com/drugs/DB11594ApprovedDomiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
Categories: Antiinfectives and Antiseptics for Local Oral TreatmentMeplazumab
go.drugbank.com/drugs/DB16465InvestigationalMeplazumab is a humanized anti-CD147 antibody being investigated as an add-on therapy in patients with COVID-19 pneumonia.
Categories: Experimental Unapproved Treatments for COVID-19Etomidate
go.drugbank.com/drugs/DB00292ApprovedInvestigationalImidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Categories: Adrenergic alpha-2 Receptor AgonistsDelandistrogene moxeparvovec
go.drugbank.com/drugs/DB16802ApprovedInvestigationalDystrophin is an essential protein responsible for muscle function; thus, patients with DMD experience a progressive deterioration of muscle mass and function. … [A260256, L47021] In November 2025, approved new safety warnings and an updated indication for Elevidys following reports of fatal liver injuries.[L54718]
Hexocyclium
go.drugbank.com/drugs/DB06787ApprovedHexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea.
Categories: Drugs for Functional Gastrointestinal DisordersPerampanel
go.drugbank.com/drugs/DB08883ApprovedInvestigationalIt is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. … Perampanel is a noncompetitive AMPA glutamate receptor antagonist.
Categories: AMPA Receptor Antagonists, Noncompetitive AMPA Glutamate Receptor AntagonistRifabutin
go.drugbank.com/drugs/DB00615ApprovedInvestigationalA broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Categories: Antiinfectives for Systemic Use, Drugs for Acid Related DisordersButamben
go.drugbank.com/drugs/DB11148ApprovedWithdrawnDue to its very low water solubility, butamben is considered to be suitable only for topical anesthesia.
TD-0903
go.drugbank.com/drugs/DB16463InvestigationalTD-0903 was investigated in clinical trials for its potential to treat acute lung injury (ALI) associated with COVID-19, including NCT04350736, NCT05091723 (a pharmacokinetics study in healthy participants
Categories: Experimental Unapproved Treatments for COVID-19Cusatuzumab
go.drugbank.com/drugs/DB15100Investigationalsyndrome (MDS) in patients unsuitable for chemotherapy. … [A241045] It is currently being investigated in the Phase 2 CULMINATE trial, in combination with [azacitidine], for the treatment of newly-diagnosed acute myeloid leukemia (AML) and high-risk myelodysplastic