Butamben is anesthesia of mucus membranes other than the eyes. Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate.
- Mechanism
- Curator reviewed · 3 references
Butamben acts by inhibiting the voltage-gated calcium channels in dorsal root ganglion neurons. The modification in this channels is thought to cause a disturbance of the channel kinetics acceleration. It is reported as well that butamben is an inhibitor of the sodium channels and a delayed rectifier of potassium currents. All the effects of butamben are performed in the root ganglion neurons which suggests that the related anesthetic effect may be caused by the reduced electrical excitability.
- Primary indication
- Butamben was indicated for the treatment of chronic pain due to its long-duration effect.Curator reviewed
- Formula / weight
- C11H15NO2 · 193.246 g/mol (avg)
- First approval
- Canada, 1994
- Also known as
- Butyl aminobenzoate
- Code names
- NSC-128464
- Brand names
Resolves to
IUWVALYLNVXWKX-UHFFFAOYSA-NSMILESCCCCOC(=O)C1=CC=C(N)C=C1What you can answer from here — as of September 23, 2026
Which drugs share a target with Butamben, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account