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Displaying results 3581 - 3590 of 10000 in total
  1. Drug

    Infliximab

    go.drugbank.com/drugs/DB00065
    ApprovedInvestigational

    There are currently two biosilimars of infliximab available in the US market that demonstrate a high degree of similarity to the reference product, Remicade. … Infliximab is produced by a recombinant cell line cultured by continuous perfusion.

    Categories: Complex Mixtures
  2. Drug

    Fomivirsen

    go.drugbank.com/drugs/DB06759
    ApprovedWithdrawn

    Fomivirsen is a antisense 21 mer phosphorothioate oligonucleotide. … It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS.

  3. Drug

    Onametostat

    go.drugbank.com/drugs/DB21480
    Investigational

    Onametostat is a small molecule drug. The usage of the INN stem '-metostat' in the name indicates that Onametostat is a histone N-methyltransferase inhibitor. … Onametostat is under investigation in clinical trial NCT06788509 (A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring).

  4. Drug

    Gamcemetinib

    go.drugbank.com/drugs/DB21624
    Investigational

    Gamcemetinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Gamcemetinib is a tyrosine kinase inhibitor. … Gamcemetinib is under investigation in clinical trial NCT04947579 (A Study of CC-99677 in Participants With Active Ankylosing Spondylitis).

  5. Drug

    Ceftibuten

    go.drugbank.com/drugs/DB01415
    ApprovedInvestigational

    Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. … It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  6. Drug

    Edoxudine

    go.drugbank.com/drugs/DB13421
    ApprovedWithdrawn

    Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. … The obtained product is an antiviral ointment.[L2407] The activity of edoxudine against herpes simplex virus was first recognized in 1967.

  7. Drug

    Avibactam

    go.drugbank.com/drugs/DB09060
    ApprovedInvestigational

    Avibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). … As there is limited clinical safety and efficacy data, Avycaz should be reserved for patients over 18 years old who have limited or not alternative treatment options.

  8. Drug

    Picafibrate

    go.drugbank.com/drugs/DB19574
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Picafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Picafibrate is a small molecule drug.

  9. Drug

    Tiafibrate

    go.drugbank.com/drugs/DB19874
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Tiafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Tiafibrate is a small molecule drug.

  10. Drug

    Iolopride I-123

    go.drugbank.com/drugs/DB20028
    Experimental

    Iolopride I-123 is a small molecule drug. The usage of the INN stem '-pride' in the name indicates that Iolopride I-123 is a sulpiride derivative and analogue.