Ceftibuten is a third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis. An antibiotic used to treat various infections in the body caused by bacteria.
- Mechanism
- Curator reviewed
Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis.
- Primary indication
- Indicated for the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.Curator reviewed · 24 structured indications
- Formula / weight
- C15H14N4O6S2 · 410.425 g/mol (avg)
- First approval
- United States, 1995
- Also known as
- Ceftibuteno · cis-ceftibuten
- Code names
- 7432-S · SCH 39720
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
UNJFKXSSGBWRBZ-BJCIPQKHSA-NSMILES[H][C@]12SCC=C(N1C(=O)[C@H]2NC(=O)C(=C/CC(O)=O)\C1=CSC(N)=N1)C(O)=OWhat you can answer from here — as of September 12, 2026
5Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
4TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Ceftibuten, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account