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Technetium Tc-99m exametazime
go.drugbank.com/drugs/DB09163ApprovedIt can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease.
Rheinanthrone
go.drugbank.com/drugs/DB13175ExperimentalRheinanthrone is the active metabolite of senna glycoside DB11365 known for its laxative effect . It is commonly produced by plants of the Rheum species .
GnRH pharmaccine
go.drugbank.com/drugs/DB05815ExperimentalThe GnRH pharmaccine consists of synthetic peptides (constructed to "look like" GnRH), which are bound chemically to a carrier and suspended in a proprietary "delivery vehicle". … The pharmaccine is administered intramuscularly to the patient by injection and induces an immune response or production of antibodies in the patient, which neutralize GnRH thus removing it from circulation
Abemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalIt is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis of cancer, or in combination with [DB00947].
CCX915
go.drugbank.com/drugs/DB05159ExperimentalThe CCR2 receptor is thought to be of central importance to inflammatory diseases, such as multiple sclerosis (MS), Type II diabetes and atherosclerosis.
Nitisinone
go.drugbank.com/drugs/DB00348ApprovedNitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1 and Alkaptonuria. It is sold under the brand names Orfadin and Harliku.
Acipimox
go.drugbank.com/drugs/DB09055ApprovedInvestigationalAcipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL.
Fenoxaprop-ethyl
go.drugbank.com/drugs/DB05252ExperimentalFenoxaprop-ethyl has been investigated to treat chronic angina, the chest pain that occurs from inadequate blood flow to the coronary arteries around the heart. … Fenoxaprop-ethyl (organic nitrate combined with L-arginine), is an oral proprietary nitrate therapeutic shown to induce coronary vasodilation while overcoming the significant problem of drug tolerance.
V1003
go.drugbank.com/drugs/DB05046ExperimentalBuprenorphine is a well-known analgesic and the intranasal formulation has the potential to provide a convenient alternative to other treatments, allowing patients to manage their post-operative pain both … prior to discharge from hospital and at home during their recovery period.
Taberminogene vadenovec
go.drugbank.com/drugs/DB05011ExperimentalTaberminogene vadenovec (EG004) is a novel product consisting of a local delivery device and a gene-based medicine, being developed to prevent the blocking of veins and arteries that frequently occurs … The initial target market is haemodialysis graft access surgery, a procedure in which patients whose kidneys have failed have a plastic tube grafted between blood vessels generally in their forearm so