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Primidone
go.drugbank.com/drugs/DB00794ApprovedVet approved[L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: 2-deoxyphenobarbital, 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dioneOxfenicine
go.drugbank.com/drugs/DB04291ExperimentalOxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Synonyms: L-2-(p-hydroxyphenyl)glycine, L-4-hydroxyphenylglycineCategories: Carnitine O-Palmitoyltransferase, antagonists & inhibitors7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
go.drugbank.com/drugs/DB04342ExperimentalSynonyms: 7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic AcidS-(N-hydroxy-N-iodophenylcarbamoyl)glutathione
go.drugbank.com/drugs/DB03330ExperimentalSynonyms: (2S)-2-Amino-5-[[(2R)-1-(carboxymethylamino)-3-[(R)-hydroxy-(N-hydroxy-4-iodoanilino)methyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid, S-(N-hydroxy-N-iodophenylcarbamoyl)glutathioneProtriptyline
go.drugbank.com/drugs/DB00344ApprovedTCAs also block histamine H<sub>1</sub> receptors, alpha<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred … See toxicity section below for a complete listing of side effects. Protriptyline may be used for the treatment of depression.
Categories: P-glycoprotein inhibitorsSynonyms: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamineTW-37
go.drugbank.com/drugs/DB17059ExperimentalTW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157]
Synonyms: Benzamide, n-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl)-, N-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl)benzamideMedrysone
go.drugbank.com/drugs/DB00253ApprovedMedrysone is a corticosteroid used in ophthalmology.
Synonyms: 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dioneCategories: P-glycoprotein substrates, Cytochrome P-450 Substratesalpha-Arbutin
go.drugbank.com/drugs/DB14109ApprovedSynonyms: alpha-D-Glucopyranoside, 4-hydroxyphenyl, α-ArbutinMixtures: I-max Lightening 5Fisetin
go.drugbank.com/drugs/DB07795InvestigationalSynonyms: 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one, 3,3',4',7-TetrahydroxyflavoneCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingBomedemstat
go.drugbank.com/drugs/DB17234InvestigationalSynonyms: Benzamide, n-((1s)-4-(((1r,2s)-2-(4-fluorophenyl)cyclopropyl)amino)-1-((4-methyl-1-piperazinyl)carbonyl)butyl)-4-(1h-1,2,3-triazol-1-yl)-, N-((1s)-4-(((1r,2s)-2-(4-fluorophenyl)cyclopropyl)amino)-1-((4-methyl-1-piperazinyl)carbonyl)butyl)-4-(1h-1,2,3-triazol-1-yl)benzamideCategories: Heterocyclic Compounds, 1-Ring