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Gadopentetic acid
go.drugbank.com/drugs/DB00789ApprovedInvestigationalA complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs.
Categories: Compounds used in a research, industrial, or household settingProducts: Magnevist 2 mmol/l - Injektionslösung, MAGNEVIST FLAKON, 5 MLVinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalLike other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396]. … While these patients have a median survival of approximately 4 months and a poor prognosis [L1396], there is currently no standard therapy in patients with advanced urothelial carcinoma [A32626].
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 20',20'-difluoro-3',4'-dihydrovinorelbine, 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastineCarteolol
go.drugbank.com/drugs/DB00521ApprovedA beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: CARTEOL LP %1 UZUN ETKILI GOZ DAMLASI, 3 ML, CARTEOL LP %2 UZUN ETKILI GOZ DAMLASI, 3 MLRepinotan
go.drugbank.com/drugs/DB06506InvestigationalRepinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective properties.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingDiethylcarbamazine
go.drugbank.com/drugs/DB00711ApprovedInvestigationalVet approvedWithdrawnAn anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Categories: Heterocyclic Compounds, 1-RingLapatinib
go.drugbank.com/drugs/DB01259ApprovedInvestigationalLapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor receptor (HER1/EGFR/ERBB1) tyrosine kinases inhibitor. … Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer.
Synonyms: N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamineCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesIbandronate
go.drugbank.com/drugs/DB00710ApprovedInvestigationalIbandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid]. … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.
Mixtures: IBONE D®, IBONE D 30000Products: i-Fos (Ibandronic Acid Film Coated Tablets 150mg), BONVIVA® 3 MG/3 ML.NAV 1800
go.drugbank.com/drugs/DB05437ExperimentalRIGScan CR49, a 125I-labelled CR monoclonal antibody directed against the tumour-associated antigen TAG-72, is undergoing development with Neoprobe for the intraoperative detection of metastatic colorectal
DAS-431 IV
go.drugbank.com/drugs/DB05432ExperimentalDAS-431 IV is a dopamine D1 receptor agonist developed by DrugAbuse Sciences for the treatment of Addictions, Schizophrenia, Schizoaffective Disorders, Dementia, Parkinson's Disease, Strokes etc.
Adenosine phosphate
go.drugbank.com/drugs/DB00131ApprovedInvestigationalNutraceuticalWithdrawnAdenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]
Categories: Heterocyclic Compounds, 2-RingSynonyms: Adenosine-5'P, 5'-O-Phosphonoadenosine