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ATL1101
go.drugbank.com/drugs/DB05023ExperimentalATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, a protein involved in the regulation of cell overgrowth in psoriasis.
ANA971
go.drugbank.com/drugs/DB05127ExperimentalANA971 resulted in higher levels of isatoribine in the blood than were present after oral administration of isatoribine itself. … ANA971, an orally administered prodrug of isatoribine. Isatoribine is a nucleoside analog in development for the treatment of chronic hepatitis C virus (HCV) infection.
Sonlicromanol
go.drugbank.com/drugs/DB16333InvestigationalSonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).
Categories: Vitamin E, analogs & derivatives, Compounds used in a research, industrial, or household settingSynonyms: (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-CarboxamideIdarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
ACR-16
go.drugbank.com/drugs/DB05371InvestigationalACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled trial in patients with Huntington’s disease as well as in three Phase Ib studies within Huntington … ACR-16 is also being studied in other psychiatric and neurologic diseases.
Albumin iodinated I-125 serum
go.drugbank.com/drugs/DB09429ApprovedI-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.[L12780]
AstraZeneca COVID-19 Vaccine
go.drugbank.com/drugs/DB15656ApprovedInvestigational[L32649,L32664] In March 2021, several EU member countries halted the administration of AstraZeneca's COVID-19 Vaccine due to signals of an increased risk of blood clots associated with thrombocytopenia … across the globe, including Canada, Mexico, the UK, the EU, and Australia, amongst others.
KW-7158
go.drugbank.com/drugs/DB05498ExperimentalThe therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root ganglion
Phenoxybenzamine
go.drugbank.com/drugs/DB00925ApprovedInvestigationalAn alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Amibegron
go.drugbank.com/drugs/DB05395InvestigationalAmibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.