Search
Carisoprodol
go.drugbank.com/drugs/DB00395ApprovedJanuary 2012, this drug was classified as a Schedule IV substance under the controlled substances act in several US states due to alarming rates of abuse [A176062, A176077] despite having a low potential for … This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and codeine [FDA label, F4060, F4069].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesIfenprodil
go.drugbank.com/drugs/DB08954ApprovedInvestigationalWithdrawn[A196128] Ifenprodil is being investigated for its potential utility in treating COVID-19 in an ongoing phase 2b/3 clinical trial (NCT04382924).[L16343] … [A220143, A196128] In an unbiased screen for compounds capable of reducing cell death induced by infection with the influenza strain H5N1, ifenprodil was found to have a protective effect against H5N1-
Categories: Experimental Unapproved Treatments for COVID-19, NMDA Receptor AntagonistsAmmonia N-13
go.drugbank.com/drugs/DB09326ApprovedAmmonia N 13 Injection, USP is a positron emitting radiopharmaceutical that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging. … Ammonia N 13 Injection, USP is used for imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease
PF-06273340
go.drugbank.com/drugs/DB12269InvestigationalPf 06273340 is under investigation in clinical trial NCT01934738 (A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects
Iopromide
go.drugbank.com/drugs/DB09156ApprovedIopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. … [A225366] Although iopromide can cause several serious adverse effects, including cardiac events, thromboembolism, hypersensitivity reaction, and even death if administered intrathecally inadvertently,
Pentastarch
go.drugbank.com/drugs/DB09111ApprovedWithdrawnIt is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. … Pentastarch is an artificial colloid (hydroxyethyl starch derivative). Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation.
Tositumomab
go.drugbank.com/drugs/DB00081ApprovedWithdrawnIt is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Dronedarone
go.drugbank.com/drugs/DB04855ApprovedInvestigationalA safety concern for the risk of drug-induced hepatocellular injury has been issued following marketing of dronedarone.[L8800] … [A34604] This ultimately leads to reduced tissue accumulation of the drug and decreased risk for organ toxicities, such as thyroid and pulmonary toxicities.
Categories: Adrenergic alpha-1 Receptor Antagonists, P-glycoprotein inhibitorsSynonyms: N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide