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Magnesium Aluminum Silicate
go.drugbank.com/drugs/DB11230ApprovedWithdrawnIt is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant … It also has antacid properties and is used as a component of some over the counter antacid medications.
Lanthanum carbonate
go.drugbank.com/drugs/DB06792ApprovedIt is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. … It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and preventing its absorption in the intestine.[L50733]
Synonyms: Lanthanum(3+) carbonateBuclizine
go.drugbank.com/drugs/DB00354Approved[L6217] Following this, it was touted to be effective as an appetite stimulant in children when administered in the syrup form, however, this indication has not been validated. … [A178102] In addition to the above conditions, buclizine has been studied in the treatment of migraine attacks and in the treatment of nausea and vomiting during pregnancy. [A178105, A178108]
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazinePhentolamine
go.drugbank.com/drugs/DB00692ApprovedInvestigationalPhentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. … [L48420, L48415, L48390] Phentolamine is administered intravenously, intramuscularly, submucosally, and topically.
Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingSynonyms: 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline, 3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOLButoconazole
go.drugbank.com/drugs/DB00639ApprovedButoconazole is an imidazole antifungal used in gynecology.
Synonyms: 1-[4-(4-Chloro-phenyl)-2-(2,6-dichloro-phenylsulfanyl)-butyl]-1H-imidazoleInternational brands: Femstat 3, Mycelex-3Dengue virus serotype 4
go.drugbank.com/drugs/DB22667Approved[L53368] Qdenga was approved for use in the European Union in December 2022.[L53373] … Dengue virus serotype 4 is a serotype of _Orthoflavivirus denguei_ known to cause dengue fever.
Synonyms: Dengue virus type 4, Dengue virus serotype 4Grepafloxacin
go.drugbank.com/drugs/DB00365ApprovedWithdrawnDue to the QTc-prolonging potential, as indicated by the changes in the QT interval on the electrocardiogram, and the risk for cardiovascular adverse events, grepafloxacin was withdrawn in the United States … Grepafloxacin is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections.
Categories: Topoisomerase II Inhibitors, 4-QuinolonesSamarium (153Sm) lexidronam
go.drugbank.com/drugs/DB05273ApprovedSamarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical. … The radioactive samarium is taken up in the bone cancer area and gives off radiation that helps provide relief of pain.
Products: T-BONE KAEFFluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalFluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients. … Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: FLUVOXAMINA EG, VERLIN TABLETAS X 50 MGChymotrypsin
go.drugbank.com/drugs/DB09375ApprovedInvestigationalVet approvedWithdrawnIt is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. … Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides.
Synonyms: Chymotrypsin A, Chymotrypsin B