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Displaying results 3651 - 3660 of 7284 in total
  1. Drug

    Izuforant

    go.drugbank.com/drugs/DB21571
    Experimental

    Izuforant has a monoisotopic molecular weight of 333.03 Da. … Izuforant is a small molecule drug. The usage of the INN stem '-forant' in the name indicates that Izuforant is a histamine H4 receptor antagonist.

  2. Drug

    Inixaciclib

    go.drugbank.com/drugs/DB21584
    Experimental

    Inixaciclib has a monoisotopic molecular weight of 480.24 Da. … Inixaciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Inixaciclib is a cyclin dependant kinase inhibitor.

  3. Drug

    Culmerciclib

    go.drugbank.com/drugs/DB21600
    Investigational

    Culmerciclib has a monoisotopic molecular weight of 446.23 Da. … Culmerciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Culmerciclib is a cyclin dependant kinase inhibitor.

  4. Drug

    Monzosertib

    go.drugbank.com/drugs/DB21619
    Investigational

    Monzosertib has a monoisotopic molecular weight of 465.16 Da. … Monzosertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Monzosertib is a serine/threonine kinase inhibitor.

  5. Drug

    Votoplam

    go.drugbank.com/drugs/DB21645
    Investigational

    Votoplam is a small molecule drug. The usage of the INN stem '-plam' in the name indicates that Votoplam is a SMN2 gene splicing modulator. Votoplam has a monoisotopic molecular weight of 419.22 Da.

  6. Drug

    Potrasertib

    go.drugbank.com/drugs/DB21682
    Experimental

    Potrasertib has a monoisotopic molecular weight of 564.19 Da. … Potrasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Potrasertib is a serine/threonine kinase inhibitor.

  7. Drug

    Tigemocoxib

    go.drugbank.com/drugs/DB21699
    Experimental

    Tigemocoxib has a monoisotopic molecular weight of 334.06 Da. … Tigemocoxib is a small molecule drug. The usage of the INN stem '-coxib' in the name indicates that Tigemocoxib is a selective cyclo-oxygenase inhibitor.

  8. Target

    Mediator of RNA polymerase II transcription subunit 1

    go.drugbank.com/bio_entities/BE0004382
    TargetHumans

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. … Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general

    Synonyms: Mediator complex subunit 1, Vitamin D receptor-interacting protein complex component DRIP205
  9. Target

    Syndecan-2

    go.drugbank.com/bio_entities/BE0002116
    TargetHumans

    Cell surface proteoglycan which regulates dendritic arbor morphogenesis

    Synonyms: Heparan sulfate proteoglycan core protein
  10. Drug

    Digoxin

    go.drugbank.com/drugs/DB00390
    ApprovedInvestigational

    [A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. … [A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure.

    Categories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index