Culmerciclib

DB21600InvestigationalSmall molecule

Culmerciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Culmerciclib is a cyclin dependant kinase inhibitor. Culmerciclib has a monoisotopic molecular...

Mechanism: Pharmacologically active on Cyclin-dependent kinase 2, Cyclin-dependent kinase 6, and Cyclin-dependent kinase 4
Curator reviewed
Formula / weight: C₂₄H₂₇FN₈ · 446.534 g/mol (avg)

Resolves to

Compound

UNIIZU5GL4E4WHCAS2004705-28-4ChEMBLCHEMBL5095094ChEBI758677PubChem122544510

Structure

InChIKeyLLFOBMRPWNABCB-UHFFFAOYSA-NSMILESCC(C)C1=C2C=C(C=CC2=NN1C)C1=NC(NC2=CC=C(C=N2)N2CCNCC2)=NC=C1F

Targets

P24941CDK2Q00534CDK6P11802CDK4

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

6Clinical trialsPhase, status and sponsor resolved per trial

9+ReferencesStructured and connected to the statements they support

Which drugs share a target with Culmerciclib, and which of those have an active Phase 3 trial?

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