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Displaying results 3651 - 3660 of 10000 in total
  1. Drug

    ICA-105665

    go.drugbank.com/drugs/DB06089
    Investigational

    It is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy. … In addition, ICA-105665 has also demonstrated activity in certain models of neuropathic pain.

  2. Drug

    Triglyme

    go.drugbank.com/drugs/DB02078
    Experimental

    Triethylene glycol dimethyl ether (also called triglyme) is a glycol ether used as a solvent.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Primaquine

    go.drugbank.com/drugs/DB01087
    ApprovedInvestigational

    It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. … An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide.

  4. Drug

    Carbazochrome

    go.drugbank.com/drugs/DB09012
    ApprovedWithdrawn

    It is not FDA-approved but is available as tablets or IM/SC injections in the treatment of hemorrhages in a number of countries. … Carbazochrome has been investigated for use in the treatment of non-surgical acute uncomplicated hemorrhoids in a mixture with [DB13124], and this combination therapy demonstrated efficacy and safe tolerability

  5. Drug

    ATN-161

    go.drugbank.com/drugs/DB05491
    Investigational

    It inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. … Since the expression of alpha(5)beta(1) integrin by cancer cells and the role of this molecule in tumor angiogenesis is similar across a range of different cancers, the therapeutic benefit of ATN-161 is

  6. Drug

    AG-858

    go.drugbank.com/drugs/DB05502
    Investigational

    Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models. … AG-858 (autologous heat-shock protein 70 peptide vaccine) is a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes.

  7. Drug

    Rumex acetosella whole

    go.drugbank.com/drugs/DB14166
    ApprovedWithdrawn

    Rumex acetosella whole allergenic extract is used in allergenic testing.

  8. Drug

    Rumex crispus top

    go.drugbank.com/drugs/DB14167
    ApprovedWithdrawn

    Rumex crispus top allergenic extract is used in allergenic testing.

  9. Drug

    Salix nigra bark

    go.drugbank.com/drugs/DB14169
    ApprovedWithdrawn

    Salix nigra bark allergenic extract is used in allergenic testing.

  10. Drug

    Ellagic acid

    go.drugbank.com/drugs/DB08846
    Investigational

    In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. … Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates.