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Favipiravir
go.drugbank.com/drugs/DB12466ApprovedInvestigational[A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, and may be an alternative option for … Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.
Products: Fabiflu 200mg Tablets, AVIGAN Film-Coated Tablets 200mg (Favipiravir)Atazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationalAtazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol … and other fatty substances in the blood).
Categories: Antivirals used in combination for the treatment of HIV infections, Amino Acids, Peptides, and ProteinsProducts: VIRAZAN 300MG, REYATAZ CAPSULE 300MGLoncastuximab tesirine
go.drugbank.com/drugs/DB16222ApprovedInvestigational[L45206] This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial. … [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsMacimorelin
go.drugbank.com/drugs/DB13074ApprovedMacimorelin, developed by Aeterna Zentaris, was approved by the FDA in December 2017 under the market name Macrilen for oral solution. … They include treatment for growth retardation in children and cachexia associated with chronic disease such as AIDS and cancer.
Categories: Amino Acids, Peptides, and ProteinsDiffuse Large B-Cell Lymphoma, Not Otherwise Specified
go.drugbank.com/conditions/DBCOND0080506Drugs: Polatuzumab vedotinSynonyms: Malignant lymphoma, large cell, cleaved and noncleaved, Malignant lymphoma - large cell cleaved and non-cleavedZinc transporter ZIP10
go.drugbank.com/bio_entities/BE0009884TransporterHumansSLC39A10-SLC39A6 heterodimers play also an essential role in initiating mitosis by importing zinc into cells to initiate a pathway resulting in the onset of mitosis (PubMed:32797246). … Plays an important for both mature B-cell maintenance and humoral immune responses (By similarity).
Synonyms: Zrt- and Irt-like protein 10FT516
go.drugbank.com/drugs/DB15732InvestigationalFT516 is an investigational and engineered off-the-shelf natural killer (NK) cell therapy originating from induced pluripotent stem cells (iPSC). … This compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation.
Sugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigationalThe antibody has also been granted the Breakthrough Therapy Designation by the FDA to treat relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) and an orphan drug designation … [L32868, L32873, L53333] The antibody is produced in Chinese hamster ovary cells by recombinant DNA technology.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSodium phosphate, dibasic, unspecified form
go.drugbank.com/drugs/DB14504ApprovedMixtures: Up and Up Ready To Use Enema, Aminosyn II in DextrosePoliovirus type 3 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10797ApprovedInvestigationalPoliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis … caused by poliovirus Type 3.
Mixtures: VeroPol Injektionslösung in einer Fertigspritze, -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE