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Displaying results 3661 - 3670 of 4188 in total
  1. Drug

    APR-2020

    go.drugbank.com/drugs/DB18497
    Investigational

    APR-2020 is a CD34+ cells that have been transduced in vitro with a lentiviral vector carrying a codon-optimized sequence for expressing the wild type RPS19 protein

  2. Drug

    Cyclic GMP

    go.drugbank.com/drugs/DB02315
    Experimental

    It is a cellular regulatory agent and has been described as a second messenger. … Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)

  3. Target

    Tyrosine-protein kinase ABL2

    go.drugbank.com/bio_entities/BE0000435
    TargetHumans

    Non-receptor tyrosine-protein kinase that plays an ABL1-overlapping role in key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion and receptor en...

    Synonyms: Abelson-related gene protein
  4. Drug

    2-chloroethyl-3-sarcosinamide-1-nitrosourea

    go.drugbank.com/drugs/DB11688
    Investigational

    2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific

  5. Drug

    Nerve Growth Factor

    go.drugbank.com/drugs/DB12620
    Investigational

    Nerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, Alzheimer's Disease, Traumatic Brain Injury, Cerebral Palsy Children, and Delayed Speech Development

  6. Drug

    Bemegride

    go.drugbank.com/drugs/DB13740
    Experimental

    It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.

  7. Drug

    rAAV9-CMV-hNAGLUop

    go.drugbank.com/drugs/DB33959
    Experimental

    rAAV9-CMV-hNAGLUop is a biologic drug. rAAV9-CMV-hNAGLUop is under investigation in clinical trial NCT07818759 (Single Injection of rAAV9-CMV-hNAGLUop Gene for Patients With Mucopolysaccharidosis (MPS)

  8. Drug

    Sotrastaurin

    go.drugbank.com/drugs/DB12369
    Investigational

    Sotrastaurin has been used in trials studying the basic science and treatment of Uveal Melanoma, Richter Syndrome, Prolymphocytic Leukemia, Recurrent Mantle Cell Lymphoma, and Recurrent Small Lymphocytic

  9. Drug

    Risperidone

    go.drugbank.com/drugs/DB00734
    ApprovedInvestigational

    Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, ...

  10. Drug

    MK-0767

    go.drugbank.com/drugs/DB12055
    Investigational

    MK0767 has been used in trials studying the treatment of Dyslipidemia, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Diabetes Mellitus, Type II, among others.