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DB02315ExperimentalSmall molecule
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular... It is a cellular regulatory agent and has been described as a second messenger.
- Mechanism
- Curator reviewed
Pharmacologically active on cGMP-dependent 3',5'-cyclic phosphodiesterase
- Formula / weight
- C10H12N5O7P · 345.2053 g/mol (avg)
- Also known as
- cGMP · Cyclic guanosine monophosphate · Guanosine cyclic monophosphate
Resolves to
Structure
InChIKey
ZOOGRGPOEVQQDX-UUOKFMHZSA-NSMILESNC1=NC2=C(N=CN2[C@@H]2O[C@@H]3COP(O)(=O)O[C@H]3[C@H]2O)C(=O)N1Transporters
What you can answer from here — as of September 23, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
Which drugs share a target with Cyclic GMP, and which of those have an active Phase 3 trial?